S
Sampada B. Upadhye
Researcher at University of Mississippi
Publications - 9
Citations - 1032
Sampada B. Upadhye is an academic researcher from University of Mississippi. The author has contributed to research in topics: Solubility & Glass transition. The author has an hindex of 5, co-authored 9 publications receiving 931 citations.
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Journal ArticleDOI
Pharmaceutical Applications of Hot-Melt Extrusion: Part I
Michael M. Crowley,Feng Zhang,Michael A. Repka,Sridhar Thumma,Sampada B. Upadhye,Sunil Kumar Battu,James W. McGinity,Charles R. Martin +7 more
TL;DR: The pharmaceutical applications of hot-melt extrusion, including equipment, principles of operation, and process technology, are reviewed and the physicochemical properties of the resultant dosage forms are described.
Journal ArticleDOI
Applications of hot-melt extrusion for drug delivery.
TL;DR: The range of HME applications for pharmaceutical dosage forms, such as tablets, capsules, films and implants for drug delivery through oral, transdermal, transmucosal, transungual, as well as other routes of administration are reviewed.
Journal ArticleDOI
Preparation and Characterization of Inclusion Complexes of a Hemisuccinate Ester Prodrug of Δ9-Tetrahydrocannabinol with Modified Beta-Cyclodextrins
Sampada B. Upadhye,Swapnil J. Kulkarni,Soumyajit Majumdar,Mitchell A. Avery,Waseem Gul,Mahmoud A. ElSohly,Michael A. Repka +6 more
TL;DR: The docking studies revealed the most probable mode of binding of THC-HS with RAMEB in which the alkyl chain was submerged in the hydrophobic pocket of the CD molecule and hydrogen bonding interactions were observed between the hemisuccinate ester side chain of THC and the rim hydroxy groups of RameB.
Journal ArticleDOI
In Vitro Characterization of a Novel Polymeric System for Preparation of Amorphous Solid Drug Dispersions
TL;DR: The polymeric blend of PVAP–HPMC offers a unique formulation approach for developing amorphous solid dispersions with the flexibility towards the use of these polymers in different ratios and combined quantities depending on drug properties.
Book ChapterDOI
Properties and Applications of Polyethylene Oxide and Ethylcellulose for Tamper Resistance and Controlled Drug Delivery
TL;DR: In this article, specific pharmaceutical applications where thermal behavior of POLYOX and ethyl cellulose has been utilized in the design and manufacture of the melt-extruded dosage form, will be discussed.