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Samuel M. Cohen
Researcher at University of Nebraska Medical Center
Publications - 443
Citations - 17051
Samuel M. Cohen is an academic researcher from University of Nebraska Medical Center. The author has contributed to research in topics: Urinary bladder & Urothelium. The author has an hindex of 65, co-authored 421 publications receiving 15940 citations. Previous affiliations of Samuel M. Cohen include University of British Columbia & St Vincent Hospital.
Papers
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Journal ArticleDOI
Cell proliferation in carcinogenesis
Samuel M. Cohen,Leon B. Ellwein +1 more
TL;DR: A biologically based, computerized description of carcinogenesis was used to show that the increase in cell proliferation can account for the carcinogenicity of nongenotoxic compounds.
Journal Article
Genetic errors, cell proliferation, and carcinogenesis
Samuel M. Cohen,Leon B. Ellwein +1 more
Journal ArticleDOI
A framework for human relevance analysis of information on carcinogenic modes of action.
M. E. Meek,John R. Bucher,Samuel M. Cohen,Vicki L. Dellarco,Richard N. Hill,Lois D. Lehman-McKeeman,David G. Longfellow,Timothy P. Pastoor,Jennifer Seed,Dorothy E. Patton +9 more
TL;DR: By providing a systematic approach to using MOA data, the HRF offers a new tool for the scientific community's overall effort to enhance the predictive power, reliability and transparency of cancer risk assessment.
Journal ArticleDOI
Epidemiology and etiology of bladder cancer
TL;DR: In developing countries, especially in the Middle East and parts of Africa, infections with members of the genus Schistosoma are responsible for a high incidence of bladder cancer-75% of which are squamous cell carcinomas.
Journal ArticleDOI
Methylated Arsenicals: The Implications of Metabolism and Carcinogenicity Studies in Rodents to Human Risk Assessment
TL;DR: Using a margin-of-exposure approach for MMAV and DMAV risk assessment is appropriate and the evidence strongly supports a nonlinear dose-response relationship for the biologic processes involved in the carcinogenicity of arsenicals.