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Samuel T. Wall

Researcher at Simula Research Laboratory

Publications -  57
Citations -  1429

Samuel T. Wall is an academic researcher from Simula Research Laboratory. The author has contributed to research in topics: Heart failure & Medicine. The author has an hindex of 19, co-authored 50 publications receiving 1210 citations. Previous affiliations of Samuel T. Wall include United States Department of Veterans Affairs & Norwegian University of Life Sciences.

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Theoretical impact of the injection of material into the myocardium: a finite element model simulation.

TL;DR: Simulations indicate that the addition of noncontractile material to a damaged left ventricular wall has important effects on cardiac mechanics, with potentially beneficial reduction of elevated myofiber stresses, as well as confounding changes to clinicalleft ventricular metrics.
Journal ArticleDOI

A Method for Automatically Optimizing Medical Devices for Treating Heart Failure: Designing Polymeric Injection Patterns

TL;DR: A finite element (FE) simulation-based method was developed in this study that can automatically optimize the injection pattern of the polymeric "inclusions" according to a specific objective function, using commercially available software tools.
Journal ArticleDOI

Biomimetic matrices for myocardial stabilization and stem cell transplantation

TL;DR: Tunable bioactive semi-interpenetrating polymer network hydrogels with matrix metalloproteinase (MMP) labile crosslinkers are developed to be used as an assistive microenvironment for transplantation of bone marrow-derived mesenchymal stem cells (BMSCs) into the infarcted myocardium to treat postinfarct cardiac injuries.
Patent

Controlling stem cell destiny with tunable matrices

TL;DR: In this article, a class of interpenetrating polymeric networks (IPNs) and semi-interpenetrating polymeric network (sIPN) which include a covalently grafted growth factor or differentiation factor for a stem cell was proposed.