S
Samuel T. Wall
Researcher at Simula Research Laboratory
Publications - 57
Citations - 1429
Samuel T. Wall is an academic researcher from Simula Research Laboratory. The author has contributed to research in topics: Heart failure & Medicine. The author has an hindex of 19, co-authored 50 publications receiving 1210 citations. Previous affiliations of Samuel T. Wall include United States Department of Veterans Affairs & Norwegian University of Life Sciences.
Papers
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Journal ArticleDOI
Theoretical impact of the injection of material into the myocardium: a finite element model simulation.
TL;DR: Simulations indicate that the addition of noncontractile material to a damaged left ventricular wall has important effects on cardiac mechanics, with potentially beneficial reduction of elevated myofiber stresses, as well as confounding changes to clinicalleft ventricular metrics.
Journal ArticleDOI
A Method for Automatically Optimizing Medical Devices for Treating Heart Failure: Designing Polymeric Injection Patterns
Jonathan F. Wenk,Samuel T. Wall,Robert C. Peterson,Sam Helgerson,Hani N. Sabbah,Mike Burger,Nielen Stander,Mark B. Ratcliffe,Julius M. Guccione +8 more
TL;DR: A finite element (FE) simulation-based method was developed in this study that can automatically optimize the injection pattern of the polymeric "inclusions" according to a specific objective function, using commercially available software tools.
Journal ArticleDOI
Biomimetic matrices for myocardial stabilization and stem cell transplantation
TL;DR: Tunable bioactive semi-interpenetrating polymer network hydrogels with matrix metalloproteinase (MMP) labile crosslinkers are developed to be used as an assistive microenvironment for transplantation of bone marrow-derived mesenchymal stem cells (BMSCs) into the infarcted myocardium to treat postinfarct cardiac injuries.
Journal ArticleDOI
Algisyl-LVR™ with coronary artery bypass grafting reduces left ventricular wall stress and improves function in the failing human heart
Lik Chuan Lee,Samuel T. Wall,Doron Klepach,Liang Ge,Zhihong Zhang,Randall J. Lee,Andrew G. Hinson,Joseph H. Gorman,Robert C. Gorman,Julius M. Guccione +9 more
TL;DR: These results support the novel concept that Algisyl-LVR™+CABG treatment leads to decreased myofiber stress, restored LV geometry and improved function.
Patent
Controlling stem cell destiny with tunable matrices
Kevin E. Healy,Beth Irwin,Jacob Freas Pollock,David V. Schaffer,Krishanu Saha,Ying Li,Samuel T. Wall +6 more
TL;DR: In this article, a class of interpenetrating polymeric networks (IPNs) and semi-interpenetrating polymeric network (sIPN) which include a covalently grafted growth factor or differentiation factor for a stem cell was proposed.