S
Sandie Sianongo
Researcher at University of Zambia
Publications - 16
Citations - 977
Sandie Sianongo is an academic researcher from University of Zambia. The author has contributed to research in topics: Nitazoxanide & Albendazole. The author has an hindex of 9, co-authored 15 publications receiving 892 citations.
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Journal ArticleDOI
Effect of nitazoxanide on morbidity and mortality in Zambian children with cryptosporidiosis: a randomised controlled trial
Beatrice Amadi,Mwiya Mwiya,John Musuku,Angela Watuka,Sandie Sianongo,Ayman Ayoub,Paul Kelly,Paul Kelly,Paul Kelly +8 more
TL;DR: A 3-day course of nitazoxanide significantly improved the resolution of diarrhoea, parasitological eradication, and mortality in HIV-seronegative, but not HIV-Seropositive, children.
Journal ArticleDOI
High dose prolonged treatment with nitazoxanide is not effective for cryptosporidiosis in HIV positive Zambian children: a randomised controlled trial
Beatrice Amadi,Mwiya Mwiya,Sandie Sianongo,Lara Payne,Angela Watuka,Max Katubulushi,Paul Kelly,Paul Kelly +7 more
TL;DR: This is the second randomised controlled trial to suggest that in Zambian children with HIV-related immunosuppression nitazoxanide does not eradicate this infection nor provide clinical symptom reduction.
Journal ArticleDOI
Intestinal and systemic infection, HIV, and mortality in Zambian children with persistent diarrhea and malnutrition.
Beatrice Amadi,Paul Kelly,Mwiya Mwiya,Elvin Mulwazi,Sandie Sianongo,Francis Changwe,Michael A. Thomson,Justina Hachungula,Angela Watuka,John A. Walker-Smith,Chifumbe Chintu +10 more
TL;DR: Although intestinal and systemic infections did not differ for HIV-seropositive and HIV-Seronegative children, HIV influenced nutritional states of all children and was associated with higher mortality.
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Cryptosporidiosis in urban Zambian children: an analysis of risk factors.
TL;DR: It is concluded that transmission of C. parvum can vary dynamically within one city and over short periods of time, and that water-borne contamination may be a substantial influence.
Journal ArticleDOI
Susceptibility to intestinal infection and diarrhoea in Zambian adults in relation to HIV status and CD4 count
Paul Kelly,Paul Kelly,Paul Kelly,Jim Todd,Sandie Sianongo,James Mwansa,Henry Sinsungwe,Max Katubulushi,Michael J.G. Farthing,Roger A Feldman +9 more
TL;DR: HIV has an impact on intestinal infection at all stages, with an increased disease-to-infection ratio, and the aggregation of disease in susceptible individuals irrespective of CD4 count suggests that this phenomenon is not a function of cell mediated immunity.