S
Sandra A. Biankin
Researcher at Westmead Hospital
Publications - 17
Citations - 1826
Sandra A. Biankin is an academic researcher from Westmead Hospital. The author has contributed to research in topics: Pancreatic cancer & Pancreas. The author has an hindex of 11, co-authored 17 publications receiving 1735 citations. Previous affiliations of Sandra A. Biankin include Johns Hopkins University & Johns Hopkins University School of Medicine.
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Journal ArticleDOI
An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms
Ralph H. Hruban,Kyoichi Takaori,David S. Klimstra,N. Volkan Adsay,Jorge Albores-Saavedra,Andrew V. Biankin,Sandra A. Biankin,Carolyn C. Compton,Noriyoshi Fukushima,Toru Furukawa,Michael Goggins,Yo Kato,Günter Klöppel,Daniel S. Longnecker,Jutta Lüttges,Anirban Maitra,G. Johan A. Offerhaus,Michio Shimizu,Suguru Yonezawa +18 more
TL;DR: The purpose of this meeting was to define an international acceptable set of diagnostic criteria for PanINs and IPMNs and to address a number of ambiguities that exist in the previously reported classification systems for these neoplasms.
Journal ArticleDOI
Aberrant p16(INK4A) and DPC4/Smad4 expression in intraductal papillary mucinous tumours of the pancreas is associated with invasive ductal adenocarcinoma.
Andrew V. Biankin,Sandra A. Biankin,James G. Kench,Adrienne Morey,C.-S. Lee,Darren R. Head,Robert P. Eckstein,Thomas B. Hugh,Susan Henshall,R. L. Sutherland +9 more
TL;DR: Aberrant protein expression of these cell cycle regulatory genes in IPMT and pancreatic intraepithelial neoplasia in the current model of pancreatic cancer progression suggest similarities in their development and may also represent the subsequent risk of invasive carcinoma.
Journal ArticleDOI
DPC4/Smad4 Expression and Outcome in Pancreatic Ductal Adenocarcinoma
Andrew V. Biankin,Adrienne Morey,C. Soon Lee,James G. Kench,Sandra A. Biankin,Henry C. Hook,Darren R. Head,Thomas B. Hugh,Robert L. Sutherland,Susan M. Henshall +9 more
TL;DR: Prognostic indicators in pancreatic cancer are poorly defined and difficult to quantify preoperatively, hence they may lead to inappropriate patient selection for treatment and accurate assessment of DPC4/Smad4 expression, unlike tumor size, margin status, and perineural invasion, does not require resection.
Journal Article
Overexpression of p21WAF1/CIP1 is an Early Event in the Development of Pancreatic Intraepithelial Neoplasia
Andrew V. Biankin,James G. Kench,Adrienne Morey,C. Soon Lee,Sandra A. Biankin,Darren R. Head,Thomas B. Hugh,Susan M. Henshall,Robert L. Sutherland +8 more
TL;DR: It is demonstrated that aberrant expression of key cell cycle regulatory genes may be important in the early development and progression of PanIN and p21(WAF1/CIP1) overexpression, independent of p53 and/or DPC4/Smad4 expression, may reflect increased Ras activity.
Journal ArticleDOI
Pancreatic intraepithelial neoplasia in association with intraductal papillary mucinous neoplasms of the pancreas: implications for disease progression and recurrence.
Andrew V. Biankin,James G. Kench,Sandra A. Biankin,C-Soon Lee,Adrienne Morey,Floriaan P. Dijkman,Maxwell J. Coleman,Robert L. Sutherland,Susan M. Henshall +8 more
TL;DR: PanIN lesions found in the ducts of a pancreas with IPMN may be relevant to the development of PC either coincident with IPMn or in the remnant pancrea after curative resection of IPMN.