Showing papers by "Sandra Mary Lima Vasconcelos published in 2011"
TL;DR: The data obtained suggest that the hypertensives were in redox imbalance, despite the possibly attenuating effect of their antihypertensive medication.
Abstract: BACKGROUND: Recent studies describe the participation of reactive oxygen and nitrogen species in hypertension. OBJECTIVE: To identify the redox imbalance in the blood of hypertensive. METHODS: Superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione (GSH), vitamin C, transferrin, ceruloplasmin, malondialdehyde (MDA) and carbonyl group were quantified in the blood of 20 hypertensives and 21 controls. The individuals had a Body Mass Index of ≥ 18.5 and ≤ 30 kg/m(2), glycemia ≤ 100 mg/dL, serum cholesterol ≤ 200 mg/dL, and were nonsmokers, non-pregnant and non-lactating women, non-users of alopurinol and probucol, with hypertensives on antihypertensive medication. All individuals underwent a preparatory period of 4 weeks without alcohol, vitamin supplements, dexamethasone and paracetamol. RESULTS: Reduced levels of CAT (p 0.013), GSH (p 0.003) and MDA (p 0.014), and high levels of GPx (p 0.001) and ceruloplasmin (p 0.015) were obtained in the hypertensive group compared with controls. A positive correlation between systolic pressure and MDA in hypertensive and diastolic pressure and CAT in controls was obtained. CONCLUSION: The data obtained suggest that the hypertensives were in redox imbalance, despite the possibly attenuating effect of their antihypertensive medication.
17 citations
TL;DR: The data obtained suggest that the hypertensives were in redox imbalance, despite the possibly attenuating effect of their antihypertensive medication.
Abstract: BACKGROUND: Recent studies describe the participation of reactive oxygen and nitrogen species in hypertension. OBJECTIVE: To identify the redox imbalance in the blood of hypertensive. METHODS: Superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione (GSH), vitamin C, transferrin, ceruloplasmin, malondialdehyde (MDA) and carbonyl group were quantified in the blood of 20 hypertensives and 21 controls. The individuals had a Body Mass Index of > 18.5 and < 30 kg/m2, glycemia < 100 mg/dL, serum cholesterol < 200 mg/dL, and were nonsmokers, non-pregnant and non-lactating women, non-users of alopurinol and probucol, with hypertensives on antihypertensive medication. All individuals underwent a preparatory period of 4 weeks without alcohol, vitamin supplements, dexamethasone and paracetamol. RESULTS: Reduced levels of CAT (p 0.013), GSH (p 0.003) and MDA (p 0.014), and high levels of GPx (p 0.001) and ceruloplasmin (p 0.015) were obtained in the hypertensive group compared with controls. A positive correlation between systolic pressure and MDA in hypertensive and diastolic pressure and CAT in controls was obtained. CONCLUSION: The data obtained suggest that the hypertensives were in redox imbalance, despite the possibly attenuating effect of their antihypertensive medication.
11 citations
TL;DR: Sandra Mary Lima Vasconcelos, Marília Oliveira Fonseca Goulart, Maria Alayde Mendonça da Silva, Mara da Silveira Benfato, Luiza Antas Rabelo, Gilberto Fontes, and Vanusa Manfredini are students at the Faculdade de Nutrição-FANUT.
Abstract: Sandra Mary Lima Vasconcelos1,2,4, Marília Oliveira Fonseca Goulart1,2, Maria Alayde Mendonça da Silva1,5, Vanusa Manfredini6, Mara da Silveira Benfato6, Luiza Antas Rabelo1,3, Gilberto Fontes1,3 Universidade Federal de Alagoas-UFAL1, Instituto de Química e Biotecnologia-IQB2, Instituto de Ciências Biológicas e da Saúde-ICBS3, Faculdade de Nutrição-FANUT4, Faculdade de Medicina-FAMED5; Maceió, AL-Brasil. Universidade Federal do Rio Grande do Sul-UFRGS6; Porto Alegre, RS-Brasil.
2 citations
TL;DR: The results do not allow us to discourage consumption in the amounts consumed by the studied population as a way to prevent cardiovascular disease, but it is clear that this line of research requires further investigation.
Abstract: OBJETIVO: Verificar o consumo da bebida cafe segundo a quantidade ingerida e os metodos de preparo, e sua associacao com o perfil lipidico serico de hipertensos e diabeticos. METODOS: Foram coletados, por meio de entrevista, dados demograficos, de estilo de vida e de consumo alimentar, aferidas medidas antropometricas e colhido sangue para analise de perfil lipidico serico. Analise descritiva, testes t de Student, qui-quadrado e de correlacao linear de Pearson foram utilizados com 5% de probabilidade de erro experimental. RESULTADOS: Foram avaliados 182 individuos hipertensos e diabeticos tipo 2, consumidores de cafe, distribuidos em dois grupos segundo o metodo de preparo da bebida: a brasileira e fervido. Os grupos foram semelhantes quanto aos dados demograficos, antropometricos, de estilo de vida, de consumo alimentar e de perfil lipidico serico. A quantidade per capita de po utilizado no metodo a brasileira e no fervido foi de M=7,52, DP=4,99g e M=7,91, DP=5,87g, respectivamente. O volume ingerido e a frequencia de consumo dos individuos do grupo a brasileira foi de M=517,3, DP=402,7mL e M=2,14, DP=1,06 vezes/dia, e para os consumidores de cafe fervido, M=513,4, DP=409,8mL e M=2,2, DP=0,94 vezes/dia. Nao houve associacao significativa entre a quantidade ingerida da bebida cafe e o perfil lipidico serico. CONCLUSAO: Nao houve associacao entre o consumo de cafe a brasileira ou fervido e o perfil lipidico serico, possivelmente em funcao da quantidade consumida e/ou da diluicao utilizada. Se, por um lado, os resultados nao permitem desestimular o consumo da bebida na quantidade ingerida pela populacao estudada, como medida de prevencao cardiovascular, por outro lado autorizam concluir que ha necessidade de avancar nessa linha de investigacao.
2 citations