Marília O. F. Goulart

TL;DR: These simple phenazines, containing polar (-Br,-I) and ionizable (-SO(3)H, -OH) groups, easily synthesized from cheap, natural or synthetic precursors (lapachol and beta-lapachone), at rather low cost, provide prototypes for development of new antimalarials aiming the chloroquine resistant parasites.

TL;DR: This systematic review discusses approaches, challenges and perspectives into the use of nontraditional antioxidant therapy on IBD, including natural and synthetic compounds in both human and animal models, to stimulate researchers to become more involved in this fruitful area.

TL;DR: In this paper, methanolic extract powders of acerola, passion fruit and pineapple industrial residues, including pulp, seeds and peel, were screened for antioxidant capacity and compared with their radical-scavenging activities (RSA) against both DPPH • and superoxide anion ( O 2 • - ) radicals, and their protective effect against liposome peroxidation, triggered by peroxyl radical.

TL;DR: The present review briefly addresses the role of hyperglycemia in OS, describes some of the more commonly used biomarkers of oxidative/nitrosative damage and includes selected examples of studies which evaluated OS biomarkers in patients with diabetes, pointing to the relevance of such biological components in general oxidative stress status of diabetes mellitus carriers.

TL;DR: This review article summarizes recent applications of electrochemical techniques to redox-active drug development and mechanistic studies and includes a general introduction to the use of electrochemistry in biology, with a focus on how electrochemical can uniquely provide both kinetic and thermodynamic information.