S
Sang Su Woo
Researcher at Seoul National University
Publications - 11
Citations - 343
Sang Su Woo is an academic researcher from Seoul National University. The author has contributed to research in topics: Secretion & Lipoteichoic acid. The author has an hindex of 8, co-authored 11 publications receiving 279 citations. Previous affiliations of Sang Su Woo include National Institutes of Health & University of Wisconsin-Madison.
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Journal ArticleDOI
A Ca2+-stimulated exosome release pathway in cancer cells is regulated by Munc13-4.
TL;DR: It is shown that acute elevation of Ca2+ in cancer cells stimulated a fivefold increase in CD63+, CD9+, and ALIX+ exosome release that was eliminated by Munc13-4 knockdown and not restored by Ca2+.
Journal ArticleDOI
Lipoteichoic acid and muramyl dipeptide synergistically induce maturation of human dendritic cells and concurrent expression of proinflammatory cytokines
Hye-Jin Kim,Jae Seung Yang,Sang Su Woo,Sun Kyung Kim,Cheol-Heui Yun,Kack-Kyun Kim,Seung Hyun Han +6 more
TL;DR: StLTA and MDP synergistically induce maturation and activation of human DC and ELISA showed that secretions of TNF‐α and IL‐12 p40, but not IL‐10, were induced in iDC by the costimulation.
Journal ArticleDOI
Induction of IL-8 expression by bacterial flagellin is mediated through lipid raft formation and intracellular TLR5 activation in A549 cells
Jintaek Im,Jun Ho Jeon,Min Kyung Cho,Sang Su Woo,Seok-Seong Kang,Cheol-Heui Yun,Kangseok Lee,Dae Kyun Chung,Seung Hyun Han,Seung Hyun Han +9 more
TL;DR: The results suggest that flagellin-induced IL-8 expression requires formation of lipid rafts, intracellular TLR activation, and subsequent activation of PKC and MAP kinases leading to the activation of the transcription factors NF-kappaB and NF-IL6 in human alveolar type II epithelial cells.
Journal ArticleDOI
Peptidoglycan-mediated IL-8 expression in human alveolar type II epithelial cells requires lipid raft formation and MAPK activation.
In Su Cheon,Sang Su Woo,Seok-Seong Kang,Jintaek Im,Cheol-Heui Yun,Dae Kyun Chung,Dong Ki Park,Seung Hyun Han,Seung Hyun Han +8 more
TL;DR: Results suggest that PGN induces IL-8 expression in a CD14-enhanced manner in human alveolar type II epithelial cells, through the formation of lipid rafts and the activation of MAP kinases, which ultimately leads to activation of AP-1, NF-kappaB, and NF-IL6.
Journal ArticleDOI
Human placenta promotes IL-8 expression through activation of JNK/SAPK and transcription factors NF-κB and AP-1 in PMA-differentiated THP-1 cells
Seok-Seong Kang,Sang Su Woo,Jintaek Im,Jae Seung Yang,Cheol-Heui Yun,Hyang Ran Ju,Chang-Gue Son,Eun-Yi Moon,Seung Hyun Han,Seung Hyun Han +9 more
TL;DR: Results suggest that HPE-induced IL-8 secretion occurs via activation of JNK/SAPK and transcription factors NF-kappaB and AP-1 in PMA-differentiated THP-1 cells.