Santosh Ramdas Borkar

TL;DR: Fluorescence intensity and lifetime decay analysis of the molecular probe 1-naphthol indicate that the interaction of FTY720 with the DMPC lipid bilayer membrane prevents partitioning of small molecules such as 1-methine to the membrane in both solid gel (SG) and liquid crystalline (LC) phases.

TL;DR: D-gluco-configured building block derived from D-(+)-gluconolactone has served as a common chiral template for the synthesis of enantiopure D- and L-xylo- configured 1,2,3,4-alkane tetrols from a common starting point.

TL;DR: In this article, the molecular level understanding of interaction between Fingolimod hydrochloride and dimyristoylphosphatidylcholine (DMPC) multilamellar vesicles (MLVs) as a drug molecule carrier was investigated by investigating the structural changes, solubilisation effect and thermotropic phase behaviour.

TL;DR: Total synthesis of naturally occurring Oxylipin has been achieved from open chain gluco-configured building block which is readily assembled from inexpensive and commercially available D-(+)-gluconolactone.

TL;DR: In this article, a series of threo - and erythro -configured open-chain trihydroxy ketones was synthesized starting from l - and d -ascorbic acid respectively as the starting material, through the use of Grignard reactions for the requisite C C bond formations.