S
Sarah F. B. McTavish
Researcher at University of Oxford
Publications - 13
Citations - 653
Sarah F. B. McTavish is an academic researcher from University of Oxford. The author has contributed to research in topics: Catecholamine & Tyrosine. The author has an hindex of 10, co-authored 13 publications receiving 629 citations. Previous affiliations of Sarah F. B. McTavish include Hammersmith Hospital & Warneford Hospital.
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Effect of a tyrosine-free amino acid mixture on regional brain catecholamine synthesis and release
TL;DR: It is indicated that administration of a tyrosine-free amino acid mixture to rats depletes brain tyrosines to cause a decrease in regional brain catecholamine synthesis and release, and dopaminergic neurones appear to be more vulnerable to tyosine depletion than noradrenergic neurone depletion.
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Reduction of brain dopamine concentration with dietary tyrosine plus phenylalanine depletion: an [11C]raclopride PET study.
TL;DR: This is the first demonstration of an effect of a dietary manipulation on brain dopamine release in humans and provides support for the further investigation of the role of dietary manipulations in the treatment of neuropsychiatric disorders.
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Propranolol reduces implicit negative racial bias
Sylvia Terbeck,Guy Kahane,Sarah F. B. McTavish,Julian Savulescu,Philip J. Cowen,Miles Hewstone +5 more
TL;DR: The results indicate that β-adrenoceptors play a role in the expression of implicit racial attitudes suggesting that noradrenaline-related emotional mechanisms may mediate negative racial bias.
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Effect of a selective 5-hydroxytryptamine reuptake inhibitor on brain extracellular noradrenaline: microdialysis studies using paroxetine
TL;DR: Despite its selectivity as a 5-HT reuptake inhibitor, paroxetine increased extracellular levels of noradrenaline in rat hippocampus following repeated administration, and the possibility that a facilitation of norADrenaline function might be involved in the antidepressant effect of parxetine, and possibly other SSRIs.
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A dose-finding study on the effects of branch chain amino acids on surrogate markers of brain dopamine function.
Harm J. Gijsman,Antonina Scarnà,Catherine J. Harmer,Sarah F. B. McTavish,John Odontiadis,Philip J. Cowen,Guy M. Goodwin +6 more
TL;DR: A drink containing branch chain amino acids is well tolerated in healthy volunteers and produces effects consistent with lowered dopamine function, which could provide a potential nutritional approach to disorders such as mania and schizophrenia.