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Sarah L. Veatch
Researcher at University of Michigan
Publications - 114
Citations - 9616
Sarah L. Veatch is an academic researcher from University of Michigan. The author has contributed to research in topics: Membrane & Vesicle. The author has an hindex of 34, co-authored 93 publications receiving 8526 citations. Previous affiliations of Sarah L. Veatch include University of British Columbia & University of Washington.
Papers
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Journal ArticleDOI
Separation of liquid phases in giant vesicles of ternary mixtures of phospholipids and cholesterol.
Sarah L. Veatch,Sarah L. Keller +1 more
TL;DR: In this article, the authors use fluorescence microscopy to directly observe liquid phases in giant unilamellar vesicles and find a simple relationship between chain melting temperature and miscibility transition temperature that holds for both phosphatidylcholine and sphingomyelin lipids.
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Seeing spots: Complex phase behavior in simple membranes
Sarah L. Veatch,Sarah L. Keller +1 more
TL;DR: The rich phase behavior observed in binary and ternary systems is described, including miscibility behavior varies with lipid type, lipid ratio, lipid oxidation, and level of impurity.
Journal ArticleDOI
Organization in lipid membranes containing cholesterol.
Sarah L. Veatch,Sarah L. Keller +1 more
TL;DR: Using fluorescence microscopy, spontaneous lateral separation in free-floating giant unilamellar vesicles is observed and correlations between miscibility in bilayers and in monolayers are established.
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Probing protein heterogeneity in the plasma membrane using PALM and pair correlation analysis
Prabuddha Sengupta,Tijana Jovanovic-Talisman,Tijana Jovanovic-Talisman,Dunja Skoko,Malte Renz,Sarah L. Veatch,Jennifer Lippincott-Schwartz +6 more
TL;DR: PC-PALM is an effective tool with broad applicability for analysis of protein heterogeneity and function, adaptable to other single-molecule strategies, and shows dramatic changes in glycosylphosphatidylinositol (GPI)-anchored protein arrangement under varying perturbations.
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Miscibility phase diagrams of giant vesicles containing sphingomyelin.
Sarah L. Veatch,Sarah L. Keller +1 more
TL;DR: Fluorescence microscopy is used to observe coexisting liquid domains in vesicles containing SM, an unsaturated phosphatidylcholine lipid (either DOPC or POPC), and cholesterol, and detail indirect evidence for a three-phase coexistence of one solid and two liquid phases.