S
Sarah P. Preheim
Researcher at Johns Hopkins University
Publications - 44
Citations - 3490
Sarah P. Preheim is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Population & Metagenomics. The author has an hindex of 22, co-authored 42 publications receiving 3028 citations. Previous affiliations of Sarah P. Preheim include Woods Hole Oceanographic Institution & Marine Biological Laboratory.
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Journal ArticleDOI
Resource partitioning and sympatric differentiation among closely related bacterioplankton.
Dana E. Hunt,Lawrence A. David,Dirk Gevers,Dirk Gevers,Sarah P. Preheim,Eric J. Alm,Eric J. Alm,Martin F. Polz +7 more
TL;DR: Spatial and temporal resource partitioning among Vibrionaceae strains coexisting in coastal bacterioplankton is described and environmental specialization may be an important correlate or even trigger of speciation among sympatric microbes.
Journal ArticleDOI
Population genomics of early events in the ecological differentiation of bacteria.
B. Jesse Shapiro,B. Jesse Shapiro,Jonathan Friedman,Otto X. Cordero,Sarah P. Preheim,Sonia Timberlake,Gitta Szabó,Martin F. Polz,Eric J. Alm +8 more
TL;DR: It is shown that in two recently diverged populations of ocean bacteria, ecological differentiation has occurred akin to a sexual mechanism: A few genome regions have swept through subpopulations in a habitat-specific manner, accompanied by gradual separation of gene pools as evidenced by increased habitat specificity of the most recent recombinations.
Population Genomics of Early Events in the Ecological Differentiation of Bacteria
B. J. Shapiro,Jonathan Friedman,Otto X. Cordero,Sarah P. Preheim,Sonia Timberlake,Gitta Szabó,Martin F. Polz,Eric J. Alm +7 more
TL;DR: This paper showed that in two recently diverged populations of ocean bacteria, ecological differentiation has occurred akin to a sexual mechanism: a few genome regions have swept through subpopulations in a habitat-specific manner, accompanied by gradual separation of gene pools as evidenced by increased habitat specificity of the most recent recombinations.
Journal ArticleDOI
Non-invasive mapping of the gastrointestinal microbiota identifies children with inflammatory bowel disease.
Eli Papa,Michael Docktor,Christopher Smillie,Sarah Weber,Sarah P. Preheim,Dirk Gevers,Georgia Giannoukos,Dawn Ciulla,Diana Tabbaa,Jay Ingram,David B. Schauer,Doyle V. Ward,Joshua R. Korzenik,Ramnik J. Xavier,Ramnik J. Xavier,Athos Bousvaros,Eric J. Alm,Eric J. Alm +17 more
TL;DR: Although this test can not replace endoscopy and histological examination as diagnostic tools, classification based on microbial diversity is an effective complementary technique for IBD detection in pediatric patients.
Journal ArticleDOI
Patterns and mechanisms of genetic and phenotypic differentiation in marine microbes
TL;DR: It is suggested that ocean bacteria follow at least two different adaptive strategies, which constrain rates and bounds of evolutionary processes: the ‘opportuni-troph’, exploiting spatially and temporally variable resources and the passive oligotroph, efficiently using low nutrient concentrations.