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Satendra Singh Gurjar

Researcher at Department of Biotechnology

Publications -  9
Citations -  408

Satendra Singh Gurjar is an academic researcher from Department of Biotechnology. The author has contributed to research in topics: Proinflammatory cytokine & Tail suspension test. The author has an hindex of 8, co-authored 9 publications receiving 291 citations. Previous affiliations of Satendra Singh Gurjar include Indian Institute of Technology Guwahati.

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Lipopolysaccharide induced anxiety- and depressive-like behaviour in mice are prevented by chronic pre-treatment of esculetin.

TL;DR: The results suggest that ESC prevented LPS-induced anxiety- and depressive-like behaviour which may be governed by inhibition of cytokine production, oxidative stress and plasma CORT level and the potential usefulness of ESC in the treatment of psychiatric disorders associated with inflammation and oxidative stress.
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Hesperidin and Silibinin Ameliorate Aluminum-Induced Neurotoxicity: Modulation of Antioxidants and Inflammatory Cytokines Level in Mice Hippocampus

TL;DR: It is indicated that hesperidin and silibinin exert neuroprotective effects against AlCl3-induced cognitive impairment and neurochemical changes, and may be attributed to the impediment of oxido-nitrosative stress and inflammation in the hippocampus.
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Sodium Phenylbutyrate and Edaravone Abrogate Chronic Restraint Stress-Induced Behavioral Deficits: Implication of Oxido-Nitrosative, Endoplasmic Reticulum Stress Cascade, and Neuroinflammation

TL;DR: Evidence is provided that SPB and edaravone exerted neuroprotective effects on CRS-induced cognitive deficits and anxiety- and depressive-like behavior, which is possibly coupled with inhibition of oxido-nitrosative stress, neuroinflammation, and ER stress cascade.
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Honokiol abrogates chronic restraint stress-induced cognitive impairment and depressive-like behaviour by blocking endoplasmic reticulum stress in the hippocampus of mice.

TL;DR: Honokiol could be an intriguing therapeutic approach in endoplasmic reticulum stress related neuro-pathophysiological conditions and the results clearly suggest the beneficial potential of honokiol in restraint stress through inhibition of proinflammatory cytokines and endoplasmsic retICulum stress.
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Beneficial effect of honokiol on lipopolysaccharide induced anxiety-like behavior and liver damage in mice.

TL;DR: The current investigation suggests that HNK provided beneficial effect against LPS-induced anxiety-like behavior and liver damage which may be governed by inhibition of cytokines production, oxidative stress and depletion of plasma BDNF level.