S
Satheesh K. Nair
Researcher at Mahatma Gandhi University
Publications - 22
Citations - 183
Satheesh K. Nair is an academic researcher from Mahatma Gandhi University. The author has contributed to research in topics: Boron trifluoride & Antimicrobial. The author has an hindex of 8, co-authored 22 publications receiving 177 citations.
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Journal ArticleDOI
Design, new synthesis, and calcilytic activity of substituted 3H-pyrimidin-4-ones.
Irina Shcherbakova,Guangfei Huang,Otto Geoffroy,Satheesh K. Nair,K. Swierczek,Manuel F. Balandrin,John Fox,William L. Heaton,Rebecca L. Conklin +8 more
TL;DR: Design, new synthesis, structure-activity relationship studies and calcium receptor antagonist (calcilytic) properties of novel 3H-pyrimidin-4-ones are described.
Journal ArticleDOI
Quaternary ammonium N,N-dichloroamines as topical, antimicrobial agents
Charles Francavilla,Eddy Low,Satheesh K. Nair,Bum Tae Kim,Timothy P. Shiau,Dmitri Debabov,Chris Celeri,Nichole J Alvarez,Ashley Houchin,Ping Xu,Ron Najafi,Rakesh K. Jain +11 more
TL;DR: A series of backbone modified and sulfonic acid replacement analogs of the authors' topical, clinical candidate were synthesized and led to the identification of quaternary ammonium N,N-dichloroamines as a new class of topical antimicrobial agents.
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N,N-Dichloroaminosulfonic acids as novel topical antimicrobial agents.
Eddy Low,Satheesh K. Nair,Timothy P. Shiau,Barbara Belisle,Dmitri Debabov,Chris Celeri,Meghan Zuck,Ron Najafi,N H Georgopapadakou,Rakesh K. Jain +9 more
TL;DR: 2-Dichloroamino-2-methyl-propane-1-sulfonic acid sodium salt, a stable derivative of endogenous N,N-dichlorotaurine, has been identified and is under development as a topical antimicrobial agent.
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Dimsyl Anion Induced Demethylation and Fragmentation Reactions of α-Oxoketenedithioacetals
Journal ArticleDOI
Stieglitz rearrangement of N,N-dichloro-β,β-disubstituted taurines under mild aqueous conditions
Timothy P. Shiau,Ashley Houchin,Satheesh K. Nair,Ping Xu,Eddy Low,Ramin Najafi,Rakesh K. Jain +6 more
TL;DR: New topical anti-infectives comprised of N,N-dichloro-beta,beta-disubstituted taurines have been examined for structure-stability relationships (SSR) based upon various alkyl, heteroalkyl and cycloalkyle beta-substitutions.