S
Satoshi Matsuzaki
Researcher at Oklahoma Medical Research Foundation
Publications - 32
Citations - 1536
Satoshi Matsuzaki is an academic researcher from Oklahoma Medical Research Foundation. The author has contributed to research in topics: Mitochondrion & Insulin. The author has an hindex of 17, co-authored 28 publications receiving 1274 citations. Previous affiliations of Satoshi Matsuzaki include University of Oklahoma.
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Journal ArticleDOI
MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca²⁺ overload and cell death.
Arin B. Aurora,Ahmed I. Mahmoud,Xiang Luo,Brett A. Johnson,Eva van Rooij,Satoshi Matsuzaki,Kenneth M. Humphries,Joseph A. Hill,Rhonda Bassel-Duby,Hesham A. Sadek,Eric N. Olson +10 more
TL;DR: A pivotal role is revealed for miR-214 as a regulator of cardiomyocyte Ca²⁺ homeostasis and survival during cardiac injury, as well as repression of several downstream effectors of Ca�⁺ signaling that mediate cell death.
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Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice
Rusty L. Montgomery,Matthew J. Potthoff,Michael Haberland,Xiaoxia Qi,Satoshi Matsuzaki,Kenneth M. Humphries,James A. Richardson,Rhonda Bassel-Duby,Eric N. Olson +8 more
TL;DR: A unique role for Hdac3 in maintenance of cardiac function and regulation of myocardial energy metabolism is revealed and can be attributed to excessive activity of the nuclear receptor PPARalpha.
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Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes
Sreemathi Logan,Gavin Pharaoh,M. Caleb Marlin,Dustin R. Masser,Satoshi Matsuzaki,Benjamin Wronowski,Alexander Yeganeh,Eileen E. Parks,Pavithra Premkumar,Julie A. Farley,Daniel Owen,Kenneth M. Humphries,Michael Kinter,Willard M. Freeman,Luke I. Szweda,Holly Van Remmen,William E. Sonntag +16 more
TL;DR: Results indicate that a reduction in IGF-1 receptor (IGFR) expression with age is associated with decline in hippocampal-dependent learning and increased gliosis, which may contribute to the pathogenesis of Alzheimer's disease and other age-associated cognitive pathologies.
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Hypoxia-inducible Factor 2α Regulates Expression of the Mitochondrial Aconitase Chaperone Protein Frataxin
Yavuz Oktay,Elhadji M. Dioum,Satoshi Matsuzaki,Kan Ding,Liang-Jun Yan,Ronald G. Haller,Luke I. Szweda,Joseph A. Garcia +7 more
TL;DR: The studies reveal that Fxn, like Sod2, is a nuclear-encoded, mitochondrial-localized HIF-2α target gene required for optimal mitochondrial homeostasis and expand upon the previously defined role of Hif-2 α in the cellular response to oxidative stress.
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Selective Inhibition of Deactivated Mitochondrial Complex I by Biguanides
TL;DR: In this article, the relative sensitivity of active/de-active complex I to biguanide-mediated inhibition and resulting superoxide radical (O₂(• )) production was determined.