S
Scott B. Kribbs
Researcher at Medical University of South Carolina
Publications - 17
Citations - 1405
Scott B. Kribbs is an academic researcher from Medical University of South Carolina. The author has contributed to research in topics: Heart failure & Hemodynamics. The author has an hindex of 10, co-authored 17 publications receiving 1364 citations.
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Journal ArticleDOI
Pathophysiologically relevant concentrations of tumor necrosis factor- α promote progressive left ventricular dysfunction and remodeling in rats
Biykem Bozkurt,Scott B. Kribbs,Fred J. Clubb,Lloyd H. Michael,Vladimir V. Didenko,Peter J. Hornsby,Yukihiro Seta,Hakan Oral,Francis G. Spinale,Douglas L. Mann +9 more
TL;DR: These studies suggest that pathophysiologically relevant concentrations of TNF-alpha are sufficient to mimic certain aspects of the phenotype observed in experimental and clinical models of heart failure.
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Matrix Metalloproteinase Inhibition During the Development of Congestive Heart Failure Effects on Left Ventricular Dimensions and Function
Francis G. Spinale,Mytsi L. Coker,Stephen R. Krombach,Rupak Mukherjee,Hussein Hallak,Ward V. Houck,Mark J. Clair,Scott B. Kribbs,Linda L. Johnson,J. Thomas Peterson,Michael R. Zile +10 more
TL;DR: Concomitant MMPi with developing CHF limited LV dilation and reduced wall stress, and it is suggested that increased myocardial MMP activity contributes to LV myocardian remodeling in developingCHF.
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Effects of Growth Hormone Supplementation on Left Ventricular Morphology and Myocyte Function With the Development of Congestive Heart Failure
Ward V. Houck,L. C. Pan,Scott B. Kribbs,Mark J. Clair,G M McDaniel,R S Krombach,W. M. Merritt,C. Pirie,Julie P. Iannini,Rupak Mukherjee,Francis G. Spinale +10 more
TL;DR: Short-term GH supplementation improved LV pump function in pacing CHF as a result of favorable effects on LV remodeling and contractile processes, and GH supplementation may serve as a novel therapeutic modality in developing CHF.
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Tranexamic acid reduces bleeding after cardiopulmonary bypass when compared to epsilon aminocaproic acid and placebo.
Mark L. Pinosky,Dan J. Kennedy,Richard L. Fishman,Scott Reeves,Calvert C. Alpert,Jodie Ecklund,Scott B. Kribbs,Francis G. Spinale,John M. Kratz,Robert Crawford,Glenn P. Gravlee,B.Hugh Dorman +11 more
TL;DR: TA was more effective in reducing blood loss postoperatively following CABG, suggesting that TA may be beneficial as an effective and inexpensive antifibrinolytic in first‐time CABGs patients.
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Angiotensin converting enzyme inhibition, AT1 receptor inhibition, and combination therapy with pacing induced heart failure: effects on left ventricular performance and regional blood flow patterns
R S Krombach,Mark J. Clair,Jennifer W. Hendrick,Ward V. Houck,James L. Zellner,Scott B. Kribbs,S. Whitebread,Rupak Mukherjee,M. de Gasparo,Francis G. Spinale +9 more
TL;DR: These findings suggest that with developing CHF, combined ACE inhibition and AT1 receptor blockade improved vascular resistive properties and regional blood flow distribution to a greater degree than that of either treatment alone.