Sean van Diepen

TL;DR: The epidemiology, pathophysiology, causes, and outcomes of cardiogenic shock are summarized; contemporary best medical, surgical, mechanical circulatory support, and palliative care practices are reviewed; the development of regionalized systems of care is advocated; and future research priorities are outlined.

TL;DR: The outcome of cardiogenic shock complicating myocardial infarction has not appreciably changed in the last 30 years despite the development of various percutaneous mechanical circulatory support options.

TL;DR: When assessed at the time of CICU admission, the SCAI CS classification, including presence or absence of CA, provided robust hospital mortality risk stratification and could be implemented as a clinical and research tool to identify, communicate, and predict the risk of death in patients with, and at risk for, CS.

TL;DR: Prophylactic levosimendan did not result in a rate of the short‐term composite end point of death, renal‐replacement therapy, perioperative myocardial infarction, or use of a mechanical cardiac assist device that was lower than the rate with placebo among patients with a reduced left ventricular ejection fraction who were undergoing cardiac surgery with the use of cardiopulmonary bypass.

TL;DR: Although out-of-hospital cardiac arrest survival varies significantly across US counties, a substantial proportion of the variation is attributable to differences in bystander response across communities.