S
Sébastien Lhomme
Researcher at French Institute of Health and Medical Research
Publications - 93
Citations - 3808
Sébastien Lhomme is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Hepatitis E virus & Hepatitis E. The author has an hindex of 28, co-authored 82 publications receiving 2937 citations. Previous affiliations of Sébastien Lhomme include The Research Institute at Nationwide Children's Hospital & University of Toulouse.
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Journal ArticleDOI
Insertions and Duplications in the Polyproline Region of the Hepatitis E Virus.
Sébastien Lhomme,Florence Nicot,Nicolas Jeanne,Chloé Dimeglio,Alain Roulet,Caroline Lefebvre,Romain Carcenac,Maxime Manno,Martine Dubois,Jean-Marie Péron,Laurent Alric,Nassim Kamar,Florence Abravanel,Florence Abravanel,Jacques Izopet,Jacques Izopet +15 more
TL;DR: This is the first description of HEV strains with genomic rearrangements in patients at the acute phase of infection; perhaps these strains are directly transmitted.
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Ribavirin therapy inhibits viral replication on patients with chronic hepatitis e virus infection.
Nassim Kamar,Lionel Rostaing,Lionel Rostaing,Florence Abravanel,Florence Abravanel,Cyril Garrouste,Sébastien Lhomme,Laure Esposito,G. Basse,Olivier Cointault,David Ribes,Marie Béatrice Nogier,Laurent Alric,Jean-Marie Peron,Jacques Izopet,Jacques Izopet +15 more
TL;DR: Ribavirin monotherapy inhibits the replication of HEV in vivo and might induce a sustained virological response in patients with chronic HEV infections.
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Hepatitis E virus strains in rabbits and evidence of a closely related strain in humans, France.
Jacques Izopet,Martine Dubois,Stéphane Bertagnoli,Sébastien Lhomme,Stéphane Marchandeau,Samuel Boucher,Nassim Kamar,Florence Abravanel,Jean-Luc Guérin +8 more
TL;DR: The host range ofHEV in Europe is expanding, and zoonotic transmission of HEV from rabbits is possible.
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Hepatitis E Virus Reinfections in Solid-Organ-Transplant Recipients Can Evolve Into Chronic Infections
Florence Abravanel,Sébastien Lhomme,Sabine Chapuy-Regaud,Jean-Michel Mansuy,Fabrice Muscari,Federico Sallusto,Lionel Rostaing,Nassim Kamar,Jacques Izopet +8 more
TL;DR: Low anti-HEV antibodies seemed not to protect solid-organ recipients, and HEV reinfection in immunocompromised patients can lead to chronic infection, as in primary infections.
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Hepatitis E virus infection without reactivation in solid-organ transplant recipients, France.
Florence Legrand-Abravanel,Nassim Kamar,Karine Sandres-Sauné,Sébastien Lhomme,Jean-Michel Mansuy,Fabrice Muscari,Federico Sallusto,Lionel Rostaing,Jacques Izopet +8 more
TL;DR: Effective prophylactic measures that include those for potential zoonotic infections should reduce the risk for HEV transmission in this population of solid-organ transplant recipients.