S
Sehwan Han
Researcher at Ajou University
Publications - 60
Citations - 1458
Sehwan Han is an academic researcher from Ajou University. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 22, co-authored 59 publications receiving 1332 citations. Previous affiliations of Sehwan Han include Inje University.
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HER2 status in pure ductal carcinoma in situ and in the intraductal and invasive components of invasive ductal carcinoma determined by fluorescence in situ hybridization and immunohistochemistry
TL;DR: The increased prevalence of HER2 amplification and overexpression in DCIS is considered to be maintained in the intraductal component of IDC; however, HER2 amplifying and overexpressing are detected much less in IDC.
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Topoisomerase II-α (topoII) and HER2 amplification in breast cancers and response to preoperative doxorubicin chemotherapy
TL;DR: The findings of the current study indicate that topoII amplification may play a role in determining chemosensitivity of breast cancers to doxorubicin chemotherapy.
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Fibroblast growth factor 21 improves insulin resistance and ameliorates renal injury in db/db mice.
Hyunwook Kim,Ji Lee,Jin Joo Cha,Young Youl Hyun,Jung Eun Kim,Mi H. Lee,Hyun Kyu Song,Deok Hwa Nam,Jee Y. Han,Sehwan Han,Kum Hyun Han,Y. S. Kang,Dae-Ryong Cha +12 more
TL;DR: The results suggest that FGF21 improves insulin resistance and protects against renal injury through both improvement of systemic metabolic alterations and antifibrotic effects in type 2 diabetic nephropathy.
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E2F1 expression is related with the poor survival of lymph node-positive breast cancer patients treated with fluorouracil, doxorubicin and cyclophosphamide.
Sehwan Han,Kyeongmee Park,Byung-Noe Bae,Ki Hwan Kim,Hong-Joo Kim,Young-Duck Kim,Hong-Yong Kim +6 more
TL;DR: E2F1 expression was significantly increased in pRB-expressing tumors and was associated with an S-phase fraction and was the only significant prognostic factor of patient outcome after FAC chemotherapy by multivariate analysis.
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Spironolactone ameliorates renal injury and connective tissue growth factor expression in type II diabetic rats
Kum Hyun Han,Young Sun Kang,Sehwan Han,Yi Hwa Jee,Mi H. Lee,Jee Young Han,Hyun Koo Kim,Young Sik Kim,Dae-Ryong Cha +8 more
TL;DR: The results suggest that the antifibrotic effects of spironolactone may be mediated by CTGF through a TGF-beta1-independent pathway in this animal model of diabetic nephropathy.