S
Seiko Tamano
Researcher at Institute of Medical Science
Publications - 57
Citations - 1296
Seiko Tamano is an academic researcher from Institute of Medical Science. The author has contributed to research in topics: No-observed-adverse-effect level & 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine. The author has an hindex of 20, co-authored 57 publications receiving 1217 citations. Previous affiliations of Seiko Tamano include Nagoya City University.
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Journal ArticleDOI
Pronounced inhibition by a natural anthocyanin, purple corn color, of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-associated colorectal carcinogenesis in male F344 rats pretreated with 1,2-dimethylhydrazine.
Akihiro Hagiwara,Kayoko Miyashita,Kayoko Miyashita,Takumi Nakanishi,Takumi Nakanishi,Masashi Sano,Seiko Tamano,Tadaomi Kadota,Takatoshi Koda,Mikio Nakamura,Katsumi Imaida,Nobuyuki Ito,Tomoyuki Shirai +12 more
TL;DR: It is demonstrated that while PhIP clearly exerts promoting effects on DMH-induced colorectal carcinogenesis, these can be reduced by 5.0% PCC in the diet, under the present experimental conditions.
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Carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the rat
Nobuyuki Ito,Ryohei Hasegawa,Katsumi Imaida,Seiko Tamano,Seiko Tamano,Akihiro Hagiwara,Akihiro Hagiwara,Masao Hirose,Tomoyuki Shirai +8 more
TL;DR: The available findings strongly suggest that 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine might be of importance as an environmental factor in the production of human cancers and that its carcinogenicity could be largely avoided by reducing intake of such compounds or by adoption of appropriate chemopreventive measures.
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Lack of effects of 1439 MHz electromagnetic near field exposure on the blood-brain barrier in immature and young rats.
Masanori Kuribayashi,Jianqing Wang,Osamu Fujiwara,Yuko Doi,Kyoko Nabae,Seiko Tamano,Tadashi Ogiso,Makoto Asamoto,Tomoyuki Shirai +8 more
TL;DR: It is suggested that local exposure of the head to 1439 MHz EMF exerts no adverse effects on the blood–brain barrier in immature and young rats.
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Lack of Adverse Effects of Whole-Body Exposure to a Mobile Telecommunication Electromagnetic Field on the Rat Fetus
Satoru Takahashi,Norio Imai,Kyoko Nabae,Kanako Wake,Hiroki Kawai,Jianqing Wang,Soichi Watanabe,Mayumi Kawabe,Osamu Fujiwara,Kumiko Ogawa,Seiko Tamano,Tomoyuki Shirai +11 more
TL;DR: Under experimental conditions, whole-body exposure to 2.14 GHz for 20 h per day during gestation and lactation did not cause any adverse effects on pregnancy or the development of rats.
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A thirteen-week oral toxicity study of annatto extract (norbixin), a natural food color extracted from the seed coat of annatto (Bixa orellana L.), in Sprague–Dawley rats
Akihiro Hagiwara,Norio Imai,Toshio Ichihara,Toshio Ichihara,Masashi Sano,Seiko Tamano,H Aoki,Kazuo Yasuhara,Takatoshi Koda,Mikio Nakamura,Tomoyuki Shirai +10 more
TL;DR: The No-Observed-Adverse-Effect-Level (NOAEL) was judged to be a dietary level of 0.1% of annatto extract (norbixin), a natural food color, under the present experimental conditions.