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Sek-Wen Hui

Researcher at Roswell Park Cancer Institute

Publications -  9
Citations -  369

Sek-Wen Hui is an academic researcher from Roswell Park Cancer Institute. The author has contributed to research in topics: Bilayer & Phosphatidylcholine. The author has an hindex of 8, co-authored 9 publications receiving 358 citations.

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Effects of lipid packing on polymorphic phase behavior and membrane properties.

TL;DR: The protein/lipid ratio and phospholipid/cholesterol ratio were found to have a positive and a negative correlation, respectively, with the latent bending energy of theospholipids, suggesting the energy expense in conforming to a bilayer phase may be an important physical parameter regarding the activity and the biogenesis of membranes.
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Induction of cytotoxic T-lymphocytes by electroporation-enhanced needle-free skin immunization

TL;DR: Peptide- specific CTL response to the vaccine delivered by needle-free electroporation/electro-osmosis was equivalent to that delivered by intradermal injection, as determined by production of the peptide-specific IFN-gamma in ELISPOT assay.
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Direct measurement of headgroup hydration of polar lipids in inverted micelles

TL;DR: There appears to be a correlation between the number of water molecules a lipid binds to the phase preference of that lipid, and the lipids, like phosphatidylcholine, which favours the lamellar phase bind far greater number ofWater molecules as compared to those, likeosphatidylethanolamine, which favour the hexagonal phase.
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The tilting of the hydrocarbon chains in a single bilayer of phospholipid

TL;DR: The tilt angle of the hydrocarbon chains to the planes of a dipalmitoryl lecithin single bilayer and multilayers were estimated by the asymmetry of the electron diffraction patterns of respective hydrated specimens to support the conclusion that they were tilted with respect to the normal of the plane.
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Localization of lipid exchange sites between bulk lung surfactants and surface monolayer: Freeze fracture study

TL;DR: In this paper, the funnel-like structures were found in calf lung surfactants (CLS) and an extract of CLS (CLSE), as foam, to provide a model air-water interface for study of surfactant structures at the interface.