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Sen Zhang

Researcher at Peking Union Medical College

Publications -  52
Citations -  1107

Sen Zhang is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 12, co-authored 32 publications receiving 722 citations. Previous affiliations of Sen Zhang include Chinese PLA General Hospital & Tianjin University.

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GaAs/AlGaAs nanowire photodetector.

TL;DR: In this paper, a core-shell GaAs/AlGaAs nanowire photodetector operating at room temperature was demonstrated, where built-in electric fields at the semiconductor heterointerface and at the metal/semiconductor Schottky contact promote photogenerated charge separation.
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Long non-coding RNAs: From disease code to drug role.

TL;DR: This paper has reviewed the transition of lncRNAs from the role of disease coding to acting as drug candidates, including the current status and progress in preclinical research, and cutting-edge strategies for lncRNA modulation have been summarized.
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Discovery and Characterization of Novel Cyclotides Originated from Chimeric Precursors Consisting of Albumin-1 Chain a and Cyclotide Domains in the Fabaceae Family

TL;DR: It is shown unambiguously that the cliotides are cyclotides and not A1bs, as determined by their sequence homology, disulfide connectivity, and membrane active properties indicated by their antimicrobial activities against Escherichia coli and cytotoxicities to HeLa cells.
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Skimmin, a Coumarin from Hydrangea paniculata, Slows down the Progression of Membranous Glomerulonephritis by Anti-Inflammatory Effects and Inhibiting Immune Complex Deposition

TL;DR: Treatment with skimmin can significantly improve renal function and suppress the IgG deposition as well as the development of glomerular lesions in a rat model of membranous glomerulonephritis.
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Discovery of a Linear Cyclotide from the Bracelet Subfamily and Its Disulfide Mapping by Top-down Mass Spectrometry

TL;DR: Hedyotide B2 is discovered as the first linear representative of the bracelet subfamily and shares the same connectivity as conventional cyclotides, while hedyotide B1 was bactericidal to Escherichia coli and Streptococcus salivarius at low micromolar concentration.