S
Senthamaraikannan Kabilan
Researcher at Annamalai University
Publications - 145
Citations - 2025
Senthamaraikannan Kabilan is an academic researcher from Annamalai University. The author has contributed to research in topics: Antibacterial activity & Antimicrobial. The author has an hindex of 22, co-authored 141 publications receiving 1624 citations. Previous affiliations of Senthamaraikannan Kabilan include Instituto Superior de Engenharia de Lisboa.
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Comparison of Molecular Docking and Molecular Dynamics Simulations of 1,3-Thiazin-4-One with MDM2 Protein
TL;DR: The molecular docking and molecular dynamics simulations studies of 1,3–thiazin–4–one derivative with a bonafide oncogene protein MDM2 (PDB ID: 4HBM) was investigated and shows critical interactions with the important amino acid His 96 which is necessary for the inhibition ofMDM2 in both docking and dynamic studies.
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Kinetics of oxidation of some ortho, meta, and para substituted S‐phenylmercaptoacetic Acids by N‐Chloro‐3‐Methyl‐2,6‐Diphenyl piperidin‐4‐one in buffered ethanol‐water
TL;DR: In this article, the kinetics of a number of ortho, meta, and para substituted S-phenylmercaptoacetic acids by N-Chloro-3-Metyl-2,6-Diphenylpiperidin-4-one (NCP) have been studied in buffered ethanol-water (75:25 v/v) of pH 5.46.
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Synthesis and studies of semiconducting piperazine–aniline copolymer
R. Ramachandran,S. Balasubramanian,Gopalakrishnan Aridoss,Paramasivam Parthiban,Govindarajan Yamuna,Senthamaraikannan Kabilan +5 more
TL;DR: In this article, the synthesis of piperazine-aniline copolymer has been studied by using various acids using spectral and physical techniques such as UV-Visible, FT-IR, fluorescence, viscosity, density and SEM studies.
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Synthesis and antimicrobial studies of novel 2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-one 4'-phenylthiosemicarbazones.
TL;DR: New series of 2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-one 4′-phenylthiosemicarbazones (compounds 9–16) was obtained and it was proved that against bacteria, compounds 10 and 11 against Bacillus subtilis, compound 13 against Salmonella typhi, show maximum inhibition potency at low concentration and beneficial antifungal activity at minimum concentration.
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Synthesis and evaluation of the antagonistic activity of 3-acetyl-2H-benzo[g]chromen-2-one against mutant Y537S estrogen receptor alpha via E-Pharmacophore modeling, molecular docking, molecular dynamics, and in-vitro cytotoxicity studies
R. Shylaja,C. Loganathan,Senthamaraikannan Kabilan,Thangavel Mahalingam Vijayakumar,C. Meganathan +4 more
TL;DR: Coumarin scaffold can be used effectively in developing a mutant specific drug against Y537S ERα and empathize that coumarins behave as a partial antagonist and understand the mechanism by which it induces partial antagonism.