S
Setsuko K. Chambers
Researcher at University of Arizona
Publications - 158
Citations - 7181
Setsuko K. Chambers is an academic researcher from University of Arizona. The author has contributed to research in topics: Ovarian cancer & Cancer. The author has an hindex of 45, co-authored 153 publications receiving 6016 citations. Previous affiliations of Setsuko K. Chambers include Yale University & University of Rochester.
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Journal ArticleDOI
Pilot Clinical Evaluation of a Confocal Microlaparoscope for Ovarian Cancer Detection.
Matthew D. Risi,Andrew R. Rouse,Setsuko K. Chambers,Kenneth D. Hatch,Wenxin Zheng,Arthur F. Gmitro +5 more
TL;DR: It is indicated that high-resolution in vivo images obtained by the confocal laparoscope can distinguish between normal and malignant ovarian surface epithelium and in vivo performance is similar to that which can be obtained from ex vivo tissue.
Tubal origin of ovarian low-grade serous carcinoma
TL;DR: There was a progressive decrease in the population of ciliated cells, as evidenced by increasing secretory/ciliated cell ratio, from ovarian epithelial inclusions/cystadenomas to borderline tumors to low-grade serous carcinoma, indicating that the latter is a clonal expansion of secretory cells.
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An unexpected effect of glucocorticoids on stimulation of c-fms proto-oncogene expression in choriocarcinoma cells that express little glucocorticoid receptor.
TL;DR: Some JAR cells contain low levels of glucocorticoid receptor, which mediate dexamethasone stimulation of c-fms expression and confers a survival advantage to these cells by stimulating the c- fms-related invasive behavior so characteristic of choriocarcinomas.
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NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8
Annadurai Anandhan,Matthew Dodson,Aryatara Shakya,Jinjing Chen,Pengfei Liu,Yongyi Wei,Hui Tan,Qian Wang,Ziyan Jiang,Kevin Yang,Joe G. N. Garcia,Setsuko K. Chambers,Eli Chapman,Aikseng Ooi,Yang Yang-Hartwich,Brent R. Stockwell,Donna D. Zhang +16 more
TL;DR: In this paper , NRF2 maintains iron homeostasis by controlling HERC2 (E3 ubiquitin ligase for NCOA4 and FBXL5) and VAMP8 (mediates autophagosome-lysosome fusion).
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Changes in Na,K-ATPase gene expression during granulocytic differentiation of HL60 cells
TL;DR: The results show that posttranscriptional changes during induction play a major role in the differential regulation of alpha 1 and alpha 3 isoforms of Na+,K(+)-ATPase; regulation of the latter may be important for early granulocytic differentiation, or for one of the differentiated functions of mature granulocytes.