S
Setsuko K. Chambers
Researcher at University of Arizona
Publications - 158
Citations - 7181
Setsuko K. Chambers is an academic researcher from University of Arizona. The author has contributed to research in topics: Ovarian cancer & Cancer. The author has an hindex of 45, co-authored 153 publications receiving 6016 citations. Previous affiliations of Setsuko K. Chambers include Yale University & University of Rochester.
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Journal ArticleDOI
Adenocarcinoma in situ of the cervix: management and outcome.
Masoud Azodi,Setsuko K. Chambers,Thomas J. Rutherford,Ernest I. Kohorn,Peter E. Schwartz,Joseph T. Chambers +5 more
TL;DR: Women with adenocarcinoma in situ of the uterine cervix had residual disease in 31% of cases with negative margins in cone biopsies and/or with negative ECCs and in 56% of Cases with positive endocervical margins.
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Allelic loss in ovarian cancer
Teresa L. Yang-Feng,Hong Han,Kuang‐Chao ‐C Chen,Shi‐Bo ‐B Li,Elizabeth B. Claus,Maria Luisa Carcangiu,Setsuko K. Chambers,Joseph T. Chambers,Peter E. Schwartz +8 more
TL;DR: The findings indicate that multiple tumor‐suppressor genes for ovarian cancer possibly exist on chromosomes 13q, 17, and/or Xp and provide the basis for the identification of candidate gene(s) associated with ovarian cancer.
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Glyceraldehyde-3-phosphate dehydrogenase binds to the AU-Rich 3' untranslated region of colony-stimulating factor-1 (CSF-1) messenger RNA in human ovarian cancer cells: possible role in CSF-1 posttranscriptional regulation and tumor phenotype.
Nathalie Bonafé,Maureen Gilmore-Hebert,Nancy L. Folk,Masoud Azodi,Yi Zhou,Setsuko K. Chambers +5 more
TL;DR: The study identified GAPDH as an AUBP abundant in Hey cells, where it binds to CSF-1 ARE that imparts mRNA decay, leading to CSf-1 overexpression and increased metastatic properties seen in ovarian cancer.
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The multifunctional protein glyceraldehyde-3-phosphate dehydrogenase is both regulated and controls colony-stimulating factor-1 messenger RNA stability in ovarian cancer.
Yi Zhou,Xiaofang Yi,Jha'nae B. Stoffer,Nathalie Bonafé,Maureen Gilmore-Hebert,Jessica N. McAlpine,Setsuko K. Chambers +6 more
TL;DR: In ovarian cancers, it is found that GAPDH expression is regulated, and it is recognized that one of the many functions of GAPDh is to promote mRNA stability of CSF-1, an important cytokine in tumor progression.
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Extramammary Paget's Disease of the Vulva
TL;DR: Fourteen patients with extramammary Paget's disease of the vulva treated at Yale-New Haven Medical Center from 1982 through 1993 were reviewed to evaluate the accuracy of methods used to delineate surgical margins and to determine if radical operations or surgical margin status was associated with likelihood of recurrence.