Seung-Mo Hong

TL;DR: The evolutionary conserved region within the ΔNp73 promoter that contains binding sites for HIC1 (hypermethylated in cancer) protein is identified, which leads to a decrease in ΔN p73 protein levels and may normally control the oncogenic potential of the ΔP73 isoform.

TL;DR: Mucinous adenocarcinoma is histologically heterogeneous and some cases exhibit signet ring cell components, which are prognostic factors for poor overall survival and recurrence-free survivals.

TL;DR: PanNET patients showing insulin or glucagon-like peptide 1 expression and increased numbers of expressed hormones had a better survival outcome by univariate analysis, whereas gastrin expression was a negative prognostic indicator in surgically resected PanNET patients.

TL;DR: Compared to pancreatic cancer cells, few genes are reactivated by DNMT1 inhibition in pancreatic CAFs suggesting these cells do not harbor many functionally important alterations in DNA methylation.

TL;DR: In this retrospective series analysis, two radiologists reviewed the CT images of 17 patients with surgically proven HPJ to determine in consensus the location, long diameter, margin, shape, contour, and growth pattern of the lesions, the presence of a duct-like structure, the lesion enhancement patterns, including the homogeneity, and the degree of contrast enhancement compared with that of the main pancreas.