Seyedeh Hoda Alavizadeh

TL;DR: A comprehensive and updated report of empirical investigations on bioactivities and biological characteristics of crocin is provided in this paper, where it is also worth noting that the crocin principle of saffron exhibited high efficacy along with no major toxicity in experimental models.

TL;DR: In vivo study in BALB/c mice showed improved pharmacokinetic parameters including maximum plasma concentration (Cmax) and time to reach the maximum concentration (Tmax) with nanomicelles as compared to free curcuminoids and two other commercial products.

TL;DR: The aim of the current review is to emphasize the requirements for developing various NDDSs including liposomes, polymeric nanoparticles, micelles, mesoporous silica nanoparticle, nanogels and prodrugs, capable of responding to TME using their Redox-sensitive moieties.

TL;DR: The results indicated that simple DOTAP nanoliposome containing 1μg/μl SLA are appropriate delivery systems to induce a Th1 type of immune response and protection against L. major infection in BALB/c mice.

TL;DR: Affibody-targeting endowed cisplatin liposomes with significantly enhanced, albeit modest, therapeutic activity in HER2-overexpressing tumor model; however, further values are yet to be determined to advance clinical translation of these targeted nanoparticulates.