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Shahanavaj Khan

Researcher at King Saud University

Publications -  40
Citations -  864

Shahanavaj Khan is an academic researcher from King Saud University. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 16, co-authored 33 publications receiving 605 citations. Previous affiliations of Shahanavaj Khan include Jamia Millia Islamia.

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FGFR a promising druggable target in cancer: Molecular biology and new drugs

Rut Porta, +13 more
- 01 May 2017 - 
TL;DR: This review summarizes the current status of treatments targeting FGFR, focusing on the trials that are evaluating the FGFR profile as inclusion criteria: Multi-Target, Pan-FGFR Inhibitors and anti-FGF (Fibroblast Growth Factor)/FGFR Monoclonal Antibodies.
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Biology, Pathophysiological Role, and Clinical Implications of Exosomes: A Critical Appraisal

Arif Tasleem Jan, +4 more
- 29 Jan 2019 - 
TL;DR: The antigen-presenting and immune-stimulatory properties of exosomes enable them to trigger anti-tumor responses, and exosome release from cancerous cells suggests they contribute to the recruitment and reconstitution of components of tumor microenvironments.
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Optimizing indomethacin-loaded chitosan nanoparticle size, encapsulation, and release using Box-Behnken experimental design.

Mohd Abul Kalam, +4 more
- 01 Jun 2016 - 
TL;DR: In vitro drug release data were fitted in different kinetic models and pattern of drug release followed Higuchi-matrix type, and factors A, B and C were found to give synergistic effect on R1, while factor A has a negative impact on R2 and R3.
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In vitro evaluation of anticancer and antibacterial activities of cobalt oxide nanoparticles

Shahanavaj Khan, +5 more
- 12 Nov 2015 - 
TL;DR: Co3O4-NPs showed promising anticancer activity against HT29 and SW620 cells with IC50 value of 2.26 and 394.5 μg/mL, respectively, however, no significant effect of Co3O5NPs was observed against bacterial strains.
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Evaluation of in vitro cytotoxicity, biocompatibility, and changes in the expression of apoptosis regulatory proteins induced by cerium oxide nanocrystals.

Shahanavaj Khan, +6 more
- 31 May 2017 - 
TL;DR: This study revealed anticancer effects of CeO2-NCs in HT29 and SW620 colorectal cancer cell lines with half-maximal inhibitory concentration values of 2.26 and 121.18 μg ml–1, respectively.