S
Shaher Bano Mirza
Researcher at COMSATS Institute of Information Technology
Publications - 7
Citations - 109
Shaher Bano Mirza is an academic researcher from COMSATS Institute of Information Technology. The author has contributed to research in topics: Docking (molecular) & Virtual screening. The author has an hindex of 5, co-authored 5 publications receiving 73 citations. Previous affiliations of Shaher Bano Mirza include Bahçeşehir University.
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Virtual screening of eighteen million compounds against dengue virus: Combined molecular docking and molecular dynamics simulations study.
TL;DR: In computational studies, proposed compounds confirm promising results against all the four serotypes of dengue virus, strengthening the opportunity of these compounds to work as potential on-shelf drugs against d Dengue virus.
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Legume genomics and transcriptomics: From classic breeding to modern technologies
Muhammad Afzal,Salem S. Alghamdi,Hussein H. Migdadi,Muhammad Altaf Khan,Nurmansyah,Shaher Bano Mirza,Shaher Bano Mirza,Ehab H. El-Harty +7 more
TL;DR: The path from classical breeding to new emerging genomics tools, which will trigger and accelerate genomics-assisted breeding for recognition of novel genes for yield and quality characters for sustainable legume crop production are presented.
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Discovery of selective dengue virus inhibitors using combination of molecular fingerprint-based virtual screening protocols, structure-based pharmacophore model development, molecular dynamics simulations and in vitro studies
Shaher Bano Mirza,Regina Ching Hua Lee,Justin Jang Hann Chu,Ramin Ekhteiari Salmas,Thomas Mavromoustakos,Serdar Durdagi +5 more
TL;DR: There is no effect seen on pre-treatment of cells with these compounds indicating that the early infection processes of virus is not affected, and the post-treated compounds after Dengue virus infection has resulted in a significant 1 log PFU/ml reduction of the virus infectious titre.
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Discovery of Klotho peptide antagonists against Wnt3 and Wnt3a target proteins using combination of protein engineering, protein–protein docking, peptide docking and molecular dynamics simulations
TL;DR: Protein–peptide docking of designed peptides of Klotho against three important domains of palmitoylated Wnt3 andWnt3a yields encouraging results and leads better understanding of the Wnt protein inhibition by proposed KlothO peptides.
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Exploring Natural Products from the Biodiversity of Pakistan for Computational Drug Discovery Studies: Collection, Optimization, Design and Development of A Chemical Database (ChemDP)
TL;DR: The Chemical Database of Pakistan (ChemDP; release 01) is a fully-referenced, evolving, web-based, virtual database which has been designed and developed to introduce natural products and their derivatives from the biodiversity of Pakistan to Global scientific communities.