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Thomas Mavromoustakos

Researcher at National and Kapodistrian University of Athens

Publications -  303
Citations -  5793

Thomas Mavromoustakos is an academic researcher from National and Kapodistrian University of Athens. The author has contributed to research in topics: Angiotensin II & Docking (molecular). The author has an hindex of 38, co-authored 287 publications receiving 5091 citations. Previous affiliations of Thomas Mavromoustakos include Athens State University & Rega Institute for Medical Research.

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An effort to understand the molecular basis of hypertension through the study of conformational analysis of losartan and sarmesin using a combination of nuclear magnetic resonance spectroscopy and theoretical calculations.

TL;DR: Findings open a new avenue for synthetic chemists to design and synthesize peptidomimetic drugs based on the C-terminal segment of the proposed model of Sarmesin, a competitive antagonist of AII, which adopts a conformation which keeps in close proximity the key amino acids Sar1 (or Arg2)-Tyr(OMe)4-His6-Phe8.
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Synthesis, pH-dependent structural characterization, and solution behavior of aqueous aluminum and gallium citrate complexes.

TL;DR: The crystal structures of 1-6 reveal mononuclear octahedral complexes of Al(III) (or Ga(III)) bound to two citrates that transform to oligonuclear 1:1 species that, in agreement with previous studies, represent the thermodynamical stable state in solution.
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Structural, compositional and acidic characteristics of nanosized amorphous or partially crystalline ZSM-5 zeolite-based materials

TL;DR: Partially crystalline and X-ray amorphous ZSM-5 zeolite-based aluminosilicates have been synthesized and thoroughly characterized by chemical analysis as mentioned in this paper.
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Functional Components of Carob Fruit: Linking the Chemical and Biological Space

TL;DR: The beneficial and health-promoting effects of carob along with the clinical trials and the drug formulations derived from carob's natural components are presented in this review.
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Computational design of novel fullerene analogues as potential HIV-1 PR inhibitors: Analysis of the binding interactions between fullerene inhibitors and HIV-1 PR residues using 3D QSAR, molecular docking and molecular dynamics simulations

TL;DR: Structural analysis of systems at catalytic and flexible flap regions of the HIV-1 PR through the simulation assisted in understanding the structural preferences of these regions, as well as, the adopted orientations of fullerene derivatives within the active site of the enzyme.