scispace - formally typeset
S

Shannon Warburton

Researcher at Merck & Co.

Publications -  5
Citations -  226

Shannon Warburton is an academic researcher from Merck & Co.. The author has contributed to research in topics: Pichia pastoris & Glycan. The author has an hindex of 4, co-authored 5 publications receiving 210 citations.

Papers
More filters
Journal ArticleDOI

Improvement of N-glycan site occupancy of therapeutic glycoproteins produced in Pichia pastoris

TL;DR: The results suggest that the glycosylation status of recombinant proteins can be improved by heterologous STT3 expression, which will allow for the customization of therapeutic protein profiles.
Journal ArticleDOI

Maximizing recombinant human serum albumin production in a Mut(s) Pichia pastoris strain.

TL;DR: It is demonstrated that induction cell density is a critical factor for high level production of rHSA under controlled specific growth rate, and higher specific productivities at higher induction cell densities and at lower specific growth rates at induction.
Journal ArticleDOI

Regulation of alcohol oxidase 1 (AOX1) promoter and peroxisome biogenesis in different fermentation processes in Pichia pastoris

TL;DR: It is suggested that the maximal production of a recombinant protein is highly dependent on methanol consumption rate that is affected by the availability of methanols and oxygen molecules.