S
Sharda Kumari
Researcher at University of Texas Southwestern Medical Center
Publications - 24
Citations - 771
Sharda Kumari is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Computer science & Platelet. The author has an hindex of 11, co-authored 15 publications receiving 663 citations. Previous affiliations of Sharda Kumari include Institute of Medical Sciences, Banaras Hindu University.
Papers
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Journal ArticleDOI
Thrombus inducing property of atomically thin graphene oxide sheets.
Sunil Kumar Singh,Manoj K. Singh,Manasa K. Nayak,Sharda Kumari,Siddhartha Shrivastava,José Grácio,Debabrata Dash +6 more
TL;DR: It is reported for the first time that atomically thin GO sheets elicited strong aggregatory response in platelets through activation of Src kinases and release of calcium from intracellular stores, raising concern on putative biomedical applications of GO in the form of diagnostic and therapeutic tools.
Thrombus Inducing Property of Atomically Thin Graphene Oxide
Sheets K. Singh,Manoj K. Singh,Manasa K. Nayak,Sharda Kumari,Siddhartha Shrivastava,Debabrata Dash +5 more
TL;DR: In this paper, it was shown that atomically thin GO sheets elicited strong aggregatory response in platelets through activation of Src kinases and release of calcium from intracellular stores, and intravenous administration of GO was found to induce extensive pulmonary thromboembolism in mice.
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Intranasal curcumin and its evaluation in murine model of asthma
Subhashini,Preeti S Chauhan,Sharda Kumari,Jarajana Pradeep Kumar,Ruchi Chawla,Debabrata Dash,Mandavi Singh,Rashmi Singh +7 more
TL;DR: Present study may prove the possibility of curcumin as complementary medication in the development of nasal drops to prevent airway inflammations and bronchoconstrictions in asthma without any side effect.
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Sirtuin Inhibition Induces Apoptosis-like Changes in Platelets and Thrombocytopenia.
TL;DR: It is demonstrated that Sirt1, Sirt2, and Sirt3 are expressed in enucleate platelets, and this results, for the first time, implicate sirtuins as a central player in the determination of platelet aging.
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Nanodiamonds activate blood platelets and induce thromboembolism
TL;DR: The findings raise concerns regarding the putative biomedical applications of NDs pertaining to diagnostics and therapeutics, and their toxicity and prothrombotic properties should be critically evaluated.