S
Shashi Bala Singh
Researcher at Defence Institute of Physiology and Allied Sciences
Publications - 261
Citations - 4857
Shashi Bala Singh is an academic researcher from Defence Institute of Physiology and Allied Sciences. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 34, co-authored 175 publications receiving 3642 citations. Previous affiliations of Shashi Bala Singh include Defence Research and Development Organisation & Government of India.
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Journal ArticleDOI
Hypobaric hypoxia induces oxidative stress in rat brain.
Panchanan Maiti,Shashi Bala Singh,Alpesh K. Sharma,Sangu Muthuraju,P.K. Banerjee,G. Ilavazhagan +5 more
TL;DR: It may be concluded that hypoxia differentially affects the antioxidant status in the cortex, hippocampus and striatum as seen by increase in free radical production, nitric oxide level, lipid peroxidation and lactate dehydrogenase levels.
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Traditional medicinal plants of cold desert Ladakh-used against kidney and urinary disorders.
TL;DR: The effectiveness of traditional system of medicine, role of Amchis in preparation of remedies according to age, sex and severity of ailment, method of preparation, doses and its administrations among tribal communities of Ladakh provides certain new information.
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Hypobaric hypoxia-induced dendritic atrophy of hippocampal neurons is associated with cognitive impairment in adult rats.
A.D.J. Titus,B. S. Shankaranarayana Rao,H.N. Harsha,K. Ramkumar,B.N. Srikumar,Shashi Bala Singh,Sumantra Chattarji,Trichur R. Raju +7 more
TL;DR: It is suggested that dendritic atrophy in the hippocampus on exposure to HBH could be one of the bases for the cognitive deficits exhibited under such conditions.
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High altitude memory impairment is due to neuronal apoptosis in hippocampus, cortex and striatum.
Panchanan Maiti,Shashi Bala Singh,Birendranath Mallick,Sangu Muthuraju,Govindasami Ilavazhagan +4 more
TL;DR: The result suggests that the apoptotic death may be involved in HA-induced memory impairment and after 7 days of exposure the effect was more pronounced but after 21 days of Exposure recovery was observed.
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Altered expression of platelet proteins and calpain activity mediate hypoxia-induced prothrombotic phenotype
Tarun Tyagi,Shadab Ahmad,Neha Gupta,Anita Sahu,Yasmin Ahmad,Velu Nair,Tathagat Chatterjee,Nitin Bajaj,Shantanu Sengupta,Lilly Ganju,Shashi Bala Singh,Mohammad Z. Ashraf +11 more
TL;DR: It is suggested that augmented calpain activity is associated with increased incidence of thrombosis under hypoxic environments and this study confirmed the prothrombotic role for calpain by an in vivo model of hypoxia-induced thromBosis.