Sheng Yao Su

TL;DR: Insight is provided into possible mechanisms underlying the pathogenesis of phosphaturic mesenchymal tumor and imply a central role of the FGF1-FGFR1 signaling pathway.

TL;DR: Interestingly, unlike the prototypical leukaemia‐inducing FGFR1 fusion genes, the FN1–FGFR1 chimeric protein was predicted to preserve its ligand‐binding domains, suggesting an advantage of the presence of its ligands in the activation of the chimeric receptor tyrosine kinase, thus effecting an autocrine or a paracrine mechanism of tumourigenesis.

TL;DR: This high-resolution profiling methodology will be useful for next-generation drug development to select drugs with higher fitness costs to resistance, and also for informing the rational use of drugs based on viral variant spectra from patients.

TL;DR: Evaluating the expression of these genes may help identify patients with progressive adenomas, helping to improve treatment, and identify genes with differential copy number alterations and progressively dysregulated expression.

TL;DR: This review will summarize the sixteen major shrimp EST studies that have been conducted to date and analyze the EST data downloaded from NCBI dbEST for the four major penaeid shrimp species and constructed a database to host all of these EST data as well as their own analysis results.