S
Shengfu Chen
Researcher at Zhejiang University
Publications - 88
Citations - 2452
Shengfu Chen is an academic researcher from Zhejiang University. The author has contributed to research in topics: Protein adsorption & Medicine. The author has an hindex of 26, co-authored 71 publications receiving 1786 citations. Previous affiliations of Shengfu Chen include Nanjing Normal University.
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Journal ArticleDOI
Investigation of the hydration of nonfouling material poly(sulfobetaine methacrylate) by low-field nuclear magnetic resonance
TL;DR: By comparing both results of polySBMA and poly(ethylene glycol) (PEG), it is found that the hydrated water molecules on the SB unit are more tightly bound than on the ethylene glycol (EG) unit before saturation, and the additional water molecules after forming the hydration layer inpolySBMA solutions show higher freedom than those in PEG.
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Binding characteristics between polyethylene glycol (PEG) and proteins in aqueous solution
Jiang Wu,Jiang Wu,Chao Zhao,Weifeng Lin,Rundong Hu,Qiuming Wang,Hong Chen,Lingyan Li,Shengfu Chen,Jie Zheng +9 more
TL;DR: This work provides new evidence to demonstrate the existence of interactions between PEG and proteins in aqueous solution, which is important not only for better understanding of the structure-activity relationship of PEG both in solution and on surfaces, but also for the rational design of new PEG-based materials for specific applications.
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Investigation of the hydration of nonfouling material poly(ethylene glycol) by low-field nuclear magnetic resonance.
Jiang Wu,Shengfu Chen +1 more
TL;DR: It is believed that the method developed could be also applied to investigate various interactions between macromolecules and other small molecules without using deuterium samples, which might open a novel route to quantitatively measure guest-host interactions in the future.
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Sulfated zwitterionic poly(sulfobetaine methacrylate) hydrogels promote complete skin regeneration.
Jiang Wu,Zecong Xiao,Anqi Chen,Huacheng He,Chaochao He,Xintao Shuai,Xiaokun Li,Shengfu Chen,Yanxian Zhang,Baiping Ren,Jie Zheng,Jie Zheng,Jian Xiao,Jian Xiao +13 more
TL;DR: Collective results indicate that SBMA hydrogels promote full-thickness excisional acute wound regeneration in mice by enhancing angiogenesis, decreasing inflammation response, and modulating macrophage polarization, which improved the overall wound healing efficiency as compared to pure PEG hydrogel.
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A facile method for polyamide membrane modification by poly(sulfobetaine methacrylate) to improve fouling resistance
TL;DR: In this paper, a zwitterionic poly(sulfobetaine methacrylate) (pSBMA) is grafted on the surface of an aromatic polyamide membrane to improve membrane fouling using surface-initiated atom transfer radical polymerization (SI-ATRP).