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Shigetada Nakanishi
Researcher at Kyoto University
Publications - 25
Citations - 14823
Shigetada Nakanishi is an academic researcher from Kyoto University. The author has contributed to research in topics: Metabotropic glutamate receptor & Metabotropic glutamate receptor 1. The author has an hindex of 24, co-authored 25 publications receiving 14631 citations.
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Cloning and expression of a cDNA encoding an endothelin receptor
TL;DR: The cloning of a complementary DNA encoding a bovine endothelin receptor is reported, which has a transmembrane topology similar to that of other G protein-coupled receptors and shows specific binding, with the highest selectivity to ET-1 in animal cells trans-fected with the cloned cDNA.
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Molecular diversity of glutamate receptors and implications for brain function.
TL;DR: The molecular and functional diversity of the glutamate receptors is reviewed and their implications for integrative brain function are discussed.
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Molecular cloning and characterization of the rat NMDA receptor
Koki Moriyoshi,Masayuki Masu,Takahiro Ishii,Ryuichi Shigemoto,Noboru Mizuno,Shigetada Nakanishi +5 more
TL;DR: A complementary DNA encoding the rat NMDA receptor has been cloned and characterized and it has been found that this protein has a significant sequence similarity to the AMPA/kainate receptors.
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Sequence and expression of a metabotropic glutamate receptor
TL;DR: The complementary DNA of a metabotropic glutamate receptor coupled to inositol phosphate/Ca2+ signal transduction has been cloned and characterized and abundant expression of this messenger RNA is observed in neuronal cells in hippocampal dentate gyrus and CA2−3 and in Cerebellar Purkinje cells, suggesting the importance of this receptor in specific hippocampal and cerebellar functions.
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A Family of Metabotropic Glutamate Receptors
TL;DR: Three cDNA clones were isolated from a rat brain cDNA library by cross-hybridization with the cDNA for a metabotropic glutamate receptor to form a novel family of G protein-coupled receptors that differ in their signal transduction and expression patterns.