Masayuki Masu

TL;DR: A complementary DNA encoding the rat NMDA receptor has been cloned and characterized and it has been found that this protein has a significant sequence similarity to the AMPA/kainate receptors.

TL;DR: The complementary DNA of a metabotropic glutamate receptor coupled to inositol phosphate/Ca2+ signal transduction has been cloned and characterized and abundant expression of this messenger RNA is observed in neuronal cells in hippocampal dentate gyrus and CA2−3 and in Cerebellar Purkinje cells, suggesting the importance of this receptor in specific hippocampal and cerebellar functions.

TL;DR: Three cDNA clones were isolated from a rat brain cDNA library by cross-hybridization with the cDNA for a metabotropic glutamate receptor to form a novel family of G protein-coupled receptors that differ in their signal transduction and expression patterns.

TL;DR: Results indicate that DCC is a receptor or a component of a receptor that mediates the effects of netrin-1 on commissural axons, and they complement genetic evidence for interactions between DCC and netrin homologs in C. elegans and Drosophila.

TL;DR: Inactivation of the murine Dcc gene caused defects in axonal projections that are similar to those observed in netrin-1-deficient mice but did not affect growth, differentiation, morphogenesis or tumorigenesis in mouse intestine, which is consistent with the hypothesis that DCC is a component of a receptor for netrin -1.