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Shiho Asaka
Researcher at Shinshu University
Publications - 46
Citations - 463
Shiho Asaka is an academic researcher from Shinshu University. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 10, co-authored 36 publications receiving 281 citations. Previous affiliations of Shiho Asaka include RMIT University & Johns Hopkins University School of Medicine.
Papers
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Journal ArticleDOI
Clinical significance of preoperative serum albumin level for prognosis in surgically resected patients with non-small cell lung cancer: Comparative study of normal lung, emphysema, and pulmonary fibrosis
Kentaro Miura,Kazutoshi Hamanaka,Tomonobu Koizumi,Yoshiaki Kitaguchi,Yukihiro Terada,Daisuke Nakamura,Hirotaka Kumeda,Hiroyuki Agatsuma,Akira Hyogotani,Satoshi Kawakami,Akihiko Yoshizawa,Shiho Asaka,Ken-ichi Ito +12 more
TL;DR: Preoperative serum albumin level was an important prognostic factor for overall survival and recurrence-free survival in patients with resected non-small cell lung cancer.
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Tumor size and computed tomography attenuation of pulmonary pure ground-glass nodules are useful for predicting pathological invasiveness.
Takashi Eguchi,Akihiko Yoshizawa,Satoshi Kawakami,Hirotaka Kumeda,Tetsuya Umesaki,Hiroyuki Agatsuma,Takao Sakaizawa,Yoshiaki Tominaga,Masayuki Toishi,Masahiro Hashizume,Takayuki Shiina,Kazuo Yoshida,Shiho Asaka,Mina Matsushita,Tomonobu Koizumi +14 more
TL;DR: Tumor size and CT attenuation were predictive factors of pathological invasiveness for pulmonary GGNs and facilitated more accurate prediction of invasive adenocarcinoma than the use of these factors independently.
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Inhibition of the MYC-Regulated Glutaminase Metabolic Axis Is an Effective Synthetic Lethal Approach for Treating Chemoresistant Ovarian Cancers.
Yao An Shen,Jiaxin Hong,Ryoichi Asaka,Shiho Asaka,Fang-Chi Hsu,Fang-Chi Hsu,Yohan Suryo Rahmanto,Jin Gyoung Jung,Yu Wei Chen,Ting Tai Yen,Alicja Tomaszewski,Cissy Zhang,Nabeel Attarwala,Angelo M. DeMarzo,Ben Davidson,Chi Mu Chuang,Chi Mu Chuang,Xi Chen,Stephanie Gaillard,Anne Le,Ie Ming Shih,Tian Li Wang +21 more
TL;DR: O ovarian cancer cells overexpressing glutaminase (GLS), a target of MYC and a key enzyme in glutaminolysis, are intrinsically resistant to platinum-based chemotherapy and are enriched with intracellular antioxidant glutathione, suggesting consideration of applying a combined therapy of GLS inhibitor and PARP inhibitor to treat chemoresistant ovarian cancers.
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Loss of ARID1A expression in endometrial samplings is associated with the risk of endometrial carcinoma.
Ting Tai Yen,Tsutomu Miyamoto,Tsutomu Miyamoto,Shiho Asaka,Shiho Asaka,M. Herman Chui,Yeh Wang,Shiou Fu Lin,Rebecca L. Stone,Amanda N. Fader,Ryoichi Asaka,Ryoichi Asaka,Hiroyasu Kashima,Tanri Shiozawa,Tian Li Wang,Ie Ming Shih,Edward J. Tanner +16 more
TL;DR: ARID1A immunostaining may correlate with malignant transformation and the presence of concurrent EEC in patients with CAH identified at pre-hysterectomy endometrial sampling.
Journal ArticleDOI
T cell-inflamed phenotype and increased Foxp3 expression in infiltrating T-cells of mismatch-repair deficient endometrial cancers.
TL;DR: The increased number of FoxP3 + regulatory T cells in mismatch repair-deficient endometrial cancers suggests that combination therapy by targeting both regulatory T cells and immune checkpoints may be warranted to improve clinical efficacy.