Shimin An

TL;DR: It is reported that ubiquitin‐specific protease 18 (USP18), a member of the deubiquitinating enzyme family, plays regulatory roles in NAFLD progression and associates with and deubiqueitinates TAK1 to protect against hepatic steatosis, insulin resistance, and the inflammatory response.

TL;DR: Hepatocyte DUSP14 is required for maintaining hepatic metabolic homeostasis and for suppressing inflammation, a novel function that relies on constraining TAK1 hyperactivation.

TL;DR: The findings suggest that NAFLD is remarkably correlated with subclinical atherosclerosis, which should be strongly advised to engage in the preventive strategies for cardiovascular diseases (CVDs).

TL;DR: Evidence is provided that EAT is strongly associated with NAFLD and other cardiovascular risk factors, and ideal cardiovascular health metrics were found to be related to EAT.

TL;DR: The results suggest that monitoring thyroid function in HOCM patients is necessary and FT3 correlated with cardiac function and could serve as an independent predictor of all-cause mortality and cardiac transplantation in patients with H OCM.