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Siyuan Wang
Researcher at Peking Union Medical College
Publications - 12
Citations - 186
Siyuan Wang is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Nonalcoholic fatty liver disease & Population. The author has an hindex of 5, co-authored 10 publications receiving 108 citations.
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Journal ArticleDOI
USP18 protects against hepatic steatosis and insulin resistance through its deubiquitinating activity
Shimin An,Ling-Ping Zhao,Li-Jun Shen,Siyuan Wang,Kuo Zhang,Yu Qi,Jilin Zheng,Xiao-Jing Zhang,Xueyong Zhu,Rong Bao,Ling Yang,Yue-Xin Lu,Zhi-Gang She,Yi-Da Tang +13 more
TL;DR: It is reported that ubiquitin‐specific protease 18 (USP18), a member of the deubiquitinating enzyme family, plays regulatory roles in NAFLD progression and associates with and deubiqueitinates TAK1 to protect against hepatic steatosis, insulin resistance, and the inflammatory response.
Journal ArticleDOI
Hepatocyte DUSP14 maintains metabolic homeostasis and suppresses inflammation in the liver.
Siyuan Wang,Zhen-Zhen Yan,Xia Yang,Shimin An,Kuo Zhang,Yu Qi,Jilin Zheng,Yan-Xiao Ji,Pi-Xiao Wang,Chun Fang,Xueyong Zhu,Li-Jun Shen,Feng-Juan Yan,Rong Bao,Song Tian,Zhi-Gang She,Yi-Da Tang +16 more
TL;DR: Hepatocyte DUSP14 is required for maintaining hepatic metabolic homeostasis and for suppressing inflammation, a novel function that relies on constraining TAK1 hyperactivation.
Journal ArticleDOI
Association between nonalcoholic fatty liver disease and subclinical atherosclerosis: a cross-sectional study on population over 40 years old.
TL;DR: The findings suggest that NAFLD is remarkably correlated with subclinical atherosclerosis, which should be strongly advised to engage in the preventive strategies for cardiovascular diseases (CVDs).
Journal ArticleDOI
Epicardial adipose tissue volume is associated with non-alcoholic fatty liver disease and cardiovascular risk factors in the general population
Xiangbin Meng,Wenyao Wang,Kuo Zhang,Yu Qi,Shimin An,Siyuan Wang,Jilin Zheng,Joyce Kong,Henghui Liu,Jing Wu,Yong Zhou,Chuanyu Gao,Yi-Da Tang +12 more
TL;DR: Evidence is provided that EAT is strongly associated with NAFLD and other cardiovascular risk factors, and ideal cardiovascular health metrics were found to be related to EAT.
Journal ArticleDOI
Prognostic Value of Free Triiodothyronine Level in Patients With Hypertrophic Obstructive Cardiomyopathy.
Kuo Zhang,Xiangbin Meng,Wenyao Wang,Jilin Zheng,Shimin An,Siyuan Wang,Yu Qi,Chuanyu Gao,Yi-Da Tang +8 more
TL;DR: The results suggest that monitoring thyroid function in HOCM patients is necessary and FT3 correlated with cardiac function and could serve as an independent predictor of all-cause mortality and cardiac transplantation in patients with H OCM.