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Shingo Sakai

Researcher at Kao Corporation

Publications -  68
Citations -  2003

Shingo Sakai is an academic researcher from Kao Corporation. The author has contributed to research in topics: Hyaluronic acid & Human skin. The author has an hindex of 21, co-authored 68 publications receiving 1752 citations. Previous affiliations of Shingo Sakai include Shizuoka University & Tohoku University.

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KIAA1199, a deafness gene of unknown function, is a new hyaluronan binding protein involved in hyaluronan depolymerization

Hiroyuki Yoshida, +10 more
- 02 Apr 2013 - 
TL;DR: KIAA1199 is a unique hyaladherin with a key role in HA catabolism in the dermis of the skin and arthritic synovium, and transfection of KIAA 1199 cDNA into cells conferred the ability to catabolize HA in an endo-β-N-acetylglucosaminidase–dependent manner via the clathrin-coated pit pathway.
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Relationship between NMF (lactate and potassium) content and the physical properties of the stratum corneum in healthy subjects.

Noriaki Nakagawa, +7 more
- 01 Mar 2004 - 
TL;DR: Changes in the physical properties of the SC induced by the extraction ofNMF were equivalent to the changes that took place from summer to winter, demonstrating the important role of NMF in thePhysical properties ofThe SC in healthy subjects.
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In vivo measurement of the water content in the dermis by confocal Raman spectroscopy.

Noriaki Nakagawa, +2 more
- 01 May 2010 - 
TL;DR: A method for measuring the dermal water content in vivo using confocal Raman spectroscopy is described and it is suggested that this instrument can measure the der mal water content.
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Putative Hyaluronan Synthase mRNA Are Expressed in Mouse Skin and TGF-β Upregulates Their Expression in Cultured Human Skin Cells

Yoshinori Sugiyama, +4 more
- 01 Feb 1998 - 
TL;DR: Differences in expression pattern of Has and has2 mRNA in mouse skin and a higher response of fibroblasts to transforming growth factor-beta suggest that Has1 and Has2 genes are regulated independently and synthesized hyaluronan may have a different function in epidermis and dermis.
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Hyaluronan Synthase 3 Regulates Hyaluronan Synthesis in Cultured Human Keratinocytes

Tetsuya Sayo, +7 more
- 01 Jan 2002 - 
TL;DR: In situ mRNA hybridization showed that mouse epidermal keratinocytes abundantly expressed HAS3 mRNA from the basal to the granular cell layers, suggesting that HAS3 functions in epidermis.