Shinji Murai

TL;DR: The selective cleavage of carbon-hydrogen bonds in organic compounds is a critical step in many organic syntheses, and is particularly important in the conversion of hydrocarbons to useful organic compounds.

TL;DR: In this paper, the cleavage and addition of ortho C−H bonds in various aromatic compounds such as ketones, esters, imines, imidates, nitrile, and aldehydes to olefins and acetlylenes can be achieved with the aid of ruthenium catalysts.

TL;DR: The ruthenium-catalyzed reaction of aromatic ketones with arylboronic acid esters (arylboronates) gave the ortho arylation product and a RuH2(CO)(PPh3)3 complex exhibited the highest catalytic activity among the complexes screened.

TL;DR: In this paper, the importance of the coordination of the oxygen atom of the ketone to ruthenium and the intervention of a cyclometallation intermediate are suggested. But the results of the deuterium labeling experiment using acetophenone-d5 and triethoxyvinylsilane are limited.

TL;DR: Catalytic reactions which involve the cleavage of an sp(3) C-H bond adjacent to a nitrogen atom in N-2-pyridynyl alkylamines are described and the substitution of an electron-withdrawing group on the pyridine ring as well as a substitution adjacent to the sp(2) nitrogen in the pyrsidine ring dramatically retards the reaction.