S
Shiyao Sui
Researcher at Harbin Medical University
Publications - 11
Citations - 647
Shiyao Sui is an academic researcher from Harbin Medical University. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 8, co-authored 11 publications receiving 366 citations.
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Inhibition of tumor propellant glutathione peroxidase 4 induces ferroptosis in cancer cells and enhances anticancer effect of cisplatin
TL;DR: GPX4 acts as an oncogene and inhibits ferroptosis in cancer cells, the anticancer effect of cisplatin can be enhanced by GPX4 inhibition, and the inhibition of GPx4 via RSL3 could enhance the anticancers effect of CISplatin in vitro and in vivo.
Journal Article
Downregulation of long noncoding RNA MALAT1 induces epithelial-to-mesenchymal transition via the PI3K-AKT pathway in breast cancer
Shouping Xu,Shiyao Sui,Jinfeng Zhang,Nan-xia Bai,Qingyu Shi,Guangwen Zhang,Song Gao,Zilong You,Chao Zhan,Feng Liu,Da Pang +10 more
TL;DR: The results indicate for the first time that MALAT1 is a novel regulator of EMT in breast cancer and may be a potential therapeutic target for breast cancer metastasis.
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Ferritinophagy is required for the induction of ferroptosis by the bromodomain protein BRD4 inhibitor (+)-JQ1 in cancer cells
TL;DR: The results showed that BRD4 expression levels were higher in cancer tissues than in normal tissues and were related to poor prognosis in cancer patients, and the anticancer effect of (+)-JQ1 was enhanced by ferroptosis inducers.
Journal ArticleDOI
Ai-lncRNA EGOT enhancing autophagy sensitizes paclitaxel cytotoxicity via upregulation of ITPR1 expression by RNA-RNA and RNA-protein interactions in human cancer
Shouping Xu,Peiyuan Wang,Jian Zhang,Hao Wu,Shiyao Sui,Jinfeng Zhang,Qin Wang,Kun Qiao,Weiwei Yang,Hongbiao Xu,Da Pang,Da Pang +11 more
TL;DR: Proper regulation of EGOT may be a novel synergistic strategy for enhancing paclitaxel sensitivity in cancer therapy and broaden comprehensive understanding of the biology function of Ai-lncRNAs.
Journal ArticleDOI
Downregulation of the long noncoding RNA EGOT correlates with malignant status and poor prognosis in breast cancer
Shouping Xu,Jinfeng Zhang,Shiyao Sui,Nan-xia Bai,Song Gao,Guangwen Zhang,Qingyu Shi,Zilong You,Chao Zhan,Da Pang,Da Pang +10 more
TL;DR: Eosinophil granule ontogeny transcript may play an important role in breast cancer progression and prognosis and may serve as a new potential prognostic target in breast patients.