Haixia Li

TL;DR: GPX4 acts as an oncogene and inhibits ferroptosis in cancer cells, the anticancer effect of cisplatin can be enhanced by GPX4 inhibition, and the inhibition of GPx4 via RSL3 could enhance the anticancers effect of CISplatin in vitro and in vivo.

TL;DR: It is found that SDT significantly inhibited endothelial cell proliferation, migration, invasion, and tube formation in tumor, and in a tumor xenograft mouse model, SDT was found to remarkably suppress tumor growth, intratumoral vascularity, and expression of vascular endothelial growth factor in tumor cells.

TL;DR: Overall survival was significantly shorter in patients with high tumour and stromal M MP-2 and MMP-9 expression, and tended to be shorter in customers with low ColIV expression, which may be a useful technique for assessing prognoses in OTSCC patients.

TL;DR: Xenograft in vivo experiments using Balb/ca nude mice and MTT assays in vitro showed that ALA-LIU therapy significantly suppressed the proliferation of SAS cells, and administration of the ROS scavenger, N-acetylcysteine (NAC), suppressed ALA -LIU-induced apoptosis and the expression of mitochondria apoptosis-related proteins, which confirmed that the ALA's induced SAS cell apoptosis is through the generation of ROS.

TL;DR: The roles of ferroptosis-associated noncoding RNAs in detail are discussed and future work regarding the interaction between nonc coding RNAs and ferroPTosis is proposed, the possible obstacles are predicted and associated solutions are put forward.