S
Sho Takagi
Researcher at Tohoku University
Publications - 49
Citations - 1505
Sho Takagi is an academic researcher from Tohoku University. The author has contributed to research in topics: Ulcerative colitis & Inflammatory bowel disease. The author has an hindex of 20, co-authored 49 publications receiving 1435 citations.
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Journal ArticleDOI
Effectiveness of an 'half elemental diet' as maintenance therapy for Crohn's disease: A randomized-controlled trial.
Sho Takagi,K. Utsunomiya,Shinichi Kuriyama,Hiroshi Yokoyama,S. Takahashi,Masahiro Iwabuchi,H. Takahashi,Yoshitaka Kinouchi,Nobuo Hiwatashi,Yuji Funayama,Iwao Sasaki,Ichiro Tsuji,Toru Shimosegawa +12 more
TL;DR: Although thiopurines have a proven role in maintenance therapy for Crohn's disease, an alternative therapy is needed for patients intolerant or resistant to thiopirines.
Journal ArticleDOI
Crohn's disease is associated with novel polymorphisms in the 5'-flanking region of the tumor necrosis factor gene
Kenichi Negoro,Yoshitaka Kinouchi,Nobuo Hiwatashi,Seiichi Takahashi,Sho Takagi,Jo Satoh,Tooru Shimosegawa,Takayoshi Toyota +7 more
TL;DR: Although the findings need to be confirmed in other populations with larger numbers of patients, TNF gene polymorphisms -1031C, -863A, and -857T are positively associated with CD; they may influence not only the susceptibility to CD but also the disease location.
Journal ArticleDOI
Ulcerative Colitis is Associated with a Promoter Polymorphism of Lipopolysaccharide Receptor Gene, CD14
Nobuya Obana,Seiichi Takahashi,Yoshitaka Kinouchi,Kenichi Negoro,Sho Takagi,Nobuo Hiwatashi,Tooru Shimosegawa +6 more
TL;DR: The promoter polymorphism of the CD14 gene at -159T plays a significant role in regulating theCD14 expression and is positively associated with ulcerative colitis, and this polymorphism may confer a genetic predisposition to ulceratives colitis.
Journal ArticleDOI
Changes of Faecal Microbiota in Patients With Crohn's Disease Treated With an Elemental Diet and Total Parenteral Nutrition
Hisashi Shiga,Takayuki Kajiura,Junko Shinozaki,Sho Takagi,Yoshitaka Kinouchi,Seiichi Takahashi,Kenichi Negoro,Katsuya Endo,Yoichi Kakuta,Manabu Suzuki,Tooru Shimosegawa +10 more
TL;DR: Faecal microbiota in Crohn's disease patients was markedly different from healthy subjects, and species diversity was reduced by total parenteral nutrition, but not by elemental diet.
Journal ArticleDOI
Clinical course and longterm prognosis of Japanese patients with Crohn's disease: predictive factors, rates of operation, and mortality.
Tatsuo Oriuchi,Nobuo Hiwatashi,Yoshitaka Kinouchi,Seiichi Takahashi,Sho Takagi,Kenichi Negoro,Tooru Shimosegawa +6 more
TL;DR: CD patients with colitis-type CD showed a better clinical course and had significantly different clinical features compared with the patients with ileitis and ileocolitis type, and the relative survival rates in Japanese patients with CD are not different from those seen in Western countries.