T
Takayoshi Toyota
Researcher at Tohoku University
Publications - 328
Citations - 10422
Takayoshi Toyota is an academic researcher from Tohoku University. The author has contributed to research in topics: Diabetes mellitus & Insulin. The author has an hindex of 51, co-authored 328 publications receiving 10096 citations. Previous affiliations of Takayoshi Toyota include Asahikawa Medical College & Yamagata University.
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Primary prevention of cardiovascular disease with pravastatin in Japan (mega study) : A prospective randomised controlled trial
Haruo Nakamura,Kikuo Arakawa,Hiroshige Itakura,Akira Kitabatake,Yoshio Goto,Takayoshi Toyota,Noriaki Nakaya,Shoji Nishimoto,Masaharu Muranaka,Akira Yamamoto,Kyoichi Mizuno,Yasuo Ohashi +11 more
TL;DR: Treatment with a low dose of pravastatin reduces the risk of coronary heart disease in Japan by much the same amount as higher doses have shown in Europe and the USA.
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Long-Term Clinical Effects of Epalrestat, an Aldose Reductase Inhibitor, on Diabetic Peripheral Neuropathy: The 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial
Nigishi Hotta,Yasuo Akanuma,Ryuzo Kawamori,Kempei Matsuoka,Yoshitomo Oka,Motoaki Shichiri,Takayoshi Toyota,Mitsuyoshi Nakashima,Isao Yoshimura,Nobuo Sakamoto,Yukio Shigeta +10 more
TL;DR: Long-term treatment with epalrestat is well tolerated and can effectively delay the progression of diabetic neuropathy and ameliorate the associated symptoms of the disease, particularly in subjects with good glycemic control and limited microangiopathy.
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Immunologic Aspects of the Nonobese Diabetic (NOD) Mouse: Abnormalities of Cellular Immunity
Shigeki Kataoka,Jo Satoh,Hiroshi Fujiya,Takayoshi Toyota,Ryuji Suzuki,Kyogo Itoh,Katsuo Kumagai +6 more
TL;DR: Investigation of the immunologic background of autoimmune diabetes mellitus in NOD mice indicates features similar to those noted in other autoimmune diseases of man and in their experimental models in laboratory animals, which may contribute to the diagnosis, treatment, and prevention of a wide variety of autoimmune diseases.
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Clinical Efficacy of Fidarestat, a Novel Aldose Reductase Inhibitor, for Diabetic Peripheral Neuropathy: A 52-week multicenter placebo-controlled double-blind parallel group study
Nigishi Hotta,Takayoshi Toyota,Kempei Matsuoka,Yukio Shigeta,Ryuichi Kikkawa,Toshio Kaneko,Akira Takahashi,Sugimura K,Yasuo Koike,Jun Ishii,Nobuo Sakamoto +10 more
TL;DR: The effects of fidarestat-treatment on nerve conduction and the subjective symptoms of diabetic neuropathy provide evidence that this treatment alters the progression of diabetes neuropathy.
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Helicobacter pylori infection prevents erosive reflux oesophagitis by decreasing gastric acid secretion
T. Koike,Shuichi Ohara,Hitoshi Sekine,Katsunori Iijima,Yasuaki Abe,Katsuaki Kato,Takayoshi Toyota,Toru Shimosegawa +7 more
TL;DR: In Japan, erosive reflux oesophagitis occurs most often in the absence of H pylori infection and gastric hyposecretion, and acid secretion was greater in patients with reflux OesophAGitis than those without oesphagitis.