S
Shona H. Lang
Researcher at York University
Publications - 50
Citations - 4256
Shona H. Lang is an academic researcher from York University. The author has contributed to research in topics: Stromal cell & Cell culture. The author has an hindex of 26, co-authored 49 publications receiving 3695 citations. Previous affiliations of Shona H. Lang include Yorkshire Cancer Research & Western General Hospital.
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Journal ArticleDOI
Cannabinoids for Medical Use: A Systematic Review and Meta-analysis.
Penny Whiting,Penny Whiting,Robert Wolff,Sohan Deshpande,Marcello Di Nisio,Steven Duffy,Adrian V. Hernandez,Adrian V. Hernandez,J. Christiaan Keurentjes,Shona H. Lang,Kate Misso,Steve Ryder,Simone Schmidlkofer,Marie Westwood,Jos Kleijnen +14 more
TL;DR: There was moderate- quality evidence to support the use of cannabinoids for the treatment of chronic pain and spasticity and low-quality evidence suggesting that cannabinoids were associated with improvements in nausea and vomiting due to chemotherapy, weight gain in HIV infection, sleep disorders, and Tourette syndrome.
Journal ArticleDOI
CD133, a novel marker for human prostatic epithelial stem cells
Gavin D. Richardson,Craig N. Robson,Shona H. Lang,David E. Neal,Norman J. Maitland,Anne T. Collins +5 more
TL;DR: In this article, a small population of human prostate basal cells express the cell surface marker CD133 and are restricted to the alpha(2)beta(1)(hi) population, previously identified as a marker of stem cells in prostate epithelia.
Journal ArticleDOI
Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions
Richard Birnie,Steven Bryce,Claire Roome,Vincent Dussupt,Alastair Droop,Shona H. Lang,Paul A. Berry,Catherine Hyde,John L. Lewis,Michael J. Stower,Norman J. Maitland,Anne T. Collins +11 more
TL;DR: An expression signature of 581 genes whose levels are significantly different in prostate cancer stem cells is described, which identified the JAK-STAT pathway and focal adhesion signaling as key processes in the biology ofcancer stem cells.
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Enhanced expression of vimentin in motile prostate cell lines and in poorly differentiated and metastatic prostate carcinoma
Shona H. Lang,Catherine Hyde,Ian N. Reid,Ian S. Hitchcock,Claire A Hart,A. A. Gordon Bryden,Jean-Marie Villette,Michael J. Stower,Norman J. Maitland +8 more
TL;DR: The metastatic potential of a series of prostate cell lines was analysed by measuring motility and invasiveness, and further correlated to the expression of epithelial differentiation markers.
Journal Article
Experimental prostate epithelial morphogenesis in response to stroma and three-dimensional matrigel culture
TL;DR: Development of a functional and morphologically correct prostate gland in vitro is dependent on extracellular matrix, steroid hormones, and factors from stromal cells and serum.