Steve Ryder

TL;DR: There was moderate- quality evidence to support the use of cannabinoids for the treatment of chronic pain and spasticity and low-quality evidence suggesting that cannabinoids were associated with improvements in nausea and vomiting due to chemotherapy, weight gain in HIV infection, sleep disorders, and Tourette syndrome.

TL;DR: This first systematic review of treatment, progression, severity and quality of life in Duchenne Muscular Dystrophy provides the most recent description of the burden, epidemiology, illness costs and treatment patterns in DMD.

TL;DR: Poor reporting of gBRCA status and basis of selection implies a need for further large well-reported BRCA mutation prevalence studies in breast cancer.

TL;DR: The available evidence suggests that ivacaftor is a clinically effective treatment for patients with CF and the G551D mutation; the high cost of ivACaftor may prove an obstacle in the uptake of this treatment.

TL;DR: A systematic review was conducted to summarise the evidence on the clinical effectiveness of Se HCAT for the assessment of BAM and the measurement of bile acid pool loss and found three studies assessing the relationship between the SeHCAT test and response to treatment with cholestyramine.