S
Shou-Wei Ding
Researcher at University of California, Riverside
Publications - 88
Citations - 17032
Shou-Wei Ding is an academic researcher from University of California, Riverside. The author has contributed to research in topics: RNA & RNA interference. The author has an hindex of 48, co-authored 81 publications receiving 14905 citations. Previous affiliations of Shou-Wei Ding include National University of Singapore & University of Adelaide.
Papers
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Journal ArticleDOI
Mouse circulating extracellular vesicles contain virus‐derived siRNAs active in antiviral immunity
Yuqiang Zhang,Yunpeng Dai,Jia-Xin Wang,Yan Xu,Zhe Li,Jinfeng Lu,Yong-Yao Xu,J. Zhong,Shou-Wei Ding,Yang Li +9 more
TL;DR: It is shown that upon antiviral RNAi activation, virus‐derived small‐interfering RNAs (vsiRNAs) from Nodamura virus, Sindbis virus, and Zika virus enter the murine bloodstream via EVs for systemic circulation, and this suggests that vaccination with live‐attenuated VSR (viral suppressor of RNAi)‐deficient mutant viruses could be a new strategy to induce immunity.
Patent
RNA silencing in animals as an antiviral defense
TL;DR: In this article, the authors proposed recombinant DNA constructs for inactivation of viral or endogenous genes in a cell, wherein the construct comprises viral sequence sufficient to activate RNA silencing, and the method for identifying inhibitors of RSI suppressors.
Journal ArticleDOI
Identification of positive and negative regulators of antiviral RNA interference in Arabidopsis thaliana
TL;DR: In this paper , the authors report two genome-wide association study screens to interrogate natural variation among wild-collected Arabidopsis thaliana accessions in quantitative resistance to the endemic cucumber mosaic virus (CMV) and demonstrate that the highest ranked gene significantly associated with resistance from both screens acts to regulate antiviral RNAi in ecotype Columbia-0.
Journal ArticleDOI
RNAi: Mechanisms, biology and applications
TL;DR: This special issue is dedicated to the rapidly expanding research field on RNA interference and focuses on one major topic of RNA silencing so that extensive literature coverage and detailed discussion on future directions are possible.
Journal ArticleDOI
Mammalian viral suppressors of RNA interference.
Wan Xiang Li,Shou-Wei Ding +1 more
TL;DR: The antiviral defense directed by the RNAi pathway employs distinct specificity and effector mechanisms compared with other immune responses as discussed by the authors , where the specificity of antiviral RNAi is programmed by siRNAs processed from virus-derived double-stranded RNA by Dicer endonuclease.