Shou-Wei Ding

TL;DR: This work identifies cooperative action of ARGONAUTE1 and ARGonAUTE2 in virus resistance conferred by 21-nucleotide virus-derived small interfering RNAs (siRNAs) and reveals that 22- nucleotide viral siRNAs do not guide efficient antiviral defense, demonstrating a qualitative difference between 21- and 22-Nucleotide classes ofSiRNAs in RNA silencing.

TL;DR: This work shows that in response to infection with Verticillium dahliae, cotton plants increase production of microRNA 166 and miR159 and export both to the fungal hyphae for specific silencing, identifying a novel defence strategy of host plants by exporting specific miRNAs to induce cross-kingdom gene silencing in pathogenic fungi and confer disease resistance.

TL;DR: Signal inactivation provides a mechanistic basis for the known role of Cmv2b in facilitating virus spread to tissues outside of the primarily infected sites and inhibits the activity of the mobile signal and interferes with DNA methylation in the nucleus.

TL;DR: It is shown that infection of hamster cells and suckling mice by Nodamura virus, a mosquito-transmissible RNA virus, requires RNAi suppression by its B2 protein, which leads to abundant production of viral siRNAs and rapid clearance of the mutant viruses in mice.

TL;DR: It is found that although a CMV mutant lacking ORF 2b accumulated in the inoculated cotyledons of cucumber plants, it was unable to spread systemically, demonstrating involvement of 2b in long distance movement.